Connective tissue Flashcards
Connective tissue (features)
- not found on body surfaces
- can be highly vascular
- is supplied by nerves (except cartilage)
Connective tissue (description)
- a major transport system of the body (e.g. blood)
- a major site of stored energy reserves (e.g. fats and adipose tissue)
Connective tissue (components)
extracellular matrix (ECM) and cells
Connective tissue (function)
binds, supports and strengths other body tissues
Extracellular matrix - ECM (Components)
Ground substances and Protein Fibres
Extracellular matrix - ECM (Structure)
largely dictates the connective tissue qualities
- cartilage = ECM is firm and rubbery
- bone = ECM is hard and flexible
Ground substance (components)
mixture of water, proteins and polysaccharides (sugars)
Sugars = ___________
glycosaminoglycans (GAGs)
Sugars (functions)
join/bind with core proteins to form proteoglycans
Sulphated GAGs (4)
Dermatan sulphate, Keratan sulphate, Chondroitin sulphate, Heparin sulphate
Dermatan sulphate
found in skin, tendons, blood vessels, heart valves
Keratan sulphate
found in bone, cartilage, cornea of the eye
Chondroitin sulphate
support + provide the adhesive features of cartilage, bone, skin, blood vessels
Non-sulphated GAGs
Hyaluronic acid
Hyaluronic acid
does not bind directly to protein backbone but is joined to various proteoglycans
Hyaluronic acid (function)
binds cells together, lubricates joints and maintains shape of eyeball
Hyalurodinase enzyme (produced by…)
white blood cells, sperm and some bacteria
Hyalurodinase enzyme (function)
- catalyse the degradation of hyaluronic acid
- makes GS more liquid so they can move more easily in it and makes access to the eggs easier for sperm
Types of Protein Fibres (3)
Collagen fibres, Reticular fibres, Elastic fibres
Collagen fibres (arrangement)
arranged in parallel bundles
Collagen fibres (features)
very strong but flexible to resist pulling forces
- preventing the CT from being torn or separated from surrounding tissues
Collagen fibres (location)
bone, cartilages, tendons and ligaments
Reticular fibres (components)
collagen with coating of glycoprotein - made by fibroblasts
Reticular fibres (function)
strength + support
- form part of the Basement Membrane
- form networks in vessels and through tissues
Elastic fibres (description)
fibrous network
Elastic fibres (key protein)
elastin surrounded by the glycoprotein fibrillin = more strength and stability
Elastic fibres (location)
skin, blood vessels and lungs
Types of Connective tissue cells
Fibroblasts vs. adipocytes (fat cells)
Fibroblasts (location)
widely distributed in the connective tissue - migratory
Fibroblasts (function)
secrete components of the matrix (ground substances and protein fibres)
Adipocytes (location)
under skin and around organs
Adipocytes (function)
stores fat (triglycerides)
Embryonic Connective Tissue (types)
Mesenchyme vs. Mucous
Mesenchyme (components)
consists of CT cells (mesenchymal cells) in a seminal fluid ground substance that contains reticular fibres
Mesenchyme (function)
gives rise to all other connective tissues
Mucous (components)
widely scattered fibroblasts embedded in jelly-like ground substance
Mucous (function)
supports the Umbilical cord of the foetus
Loose Connective Tissue (types)
Areolar, Adipose, Reticular
Areolar Connective Tissue (structure)
3 types of fibres are present (reticular, collagen, elastic)
Areolar Connective Tissue (location)
widely distributed around
Areolar Connective Tissue (function)
strength, elasticity, support
Adipose Connective Tissue (structure)
dominate by adipocytes
Adipose Connective Tissue (location)
found with the areolar connective tissue
Adipose Connective Tissue (types)
white adipose vs. brown adipose
- white = energy storage
- brown = heat production
Adipose Connective Tissue (function)
insulation, energy source, temperature control
Reticular Connective Tissue (structure)
branching + mesh-like appearance due to the reticular fibres crosslinking
Reticular Connective Tissue (location)
kidney, spleen, lymph nodes and bone marrow
Reticular Connective Tissue (function)
provides structural support for most lymphoid organs
- by creating and maintaining the networks of the fibres
Dense Connective Tissue (types)
Regular, Irregular, Elastic
Dense Regular Connective Tissue (structure)
contained tightly packed bundles of collagen fibres
Dense Regular Connective Tissue (location)
tendons, ligaments, aponeuroses
Dense Regular Connective Tissue (function)
slow healing and attachment/connection to different organs and muscles
Dense Irregular Connective Tissue (structure)
consists mostly of collagen fibres
Dense Irregular Connective Tissue (location)
dermis and eyeball’s protective white coating layer
Dense Irregular Connective Tissue (function)
strength and makes the skin resistant to tearing by stretching forces from different directions
Dense Elastic Connective Tissue (structure)
contains elastin fibres in addition to collagen fibres
Dense Elastic Connective Tissue (location)
in the walls of blood vessels, in respiratory passageways and surrounding part of the spine
Dense Elastic Connective Tissue (function)
allows tissues to regain original shape after stretching