Connective Tissue Flashcards
What is the most abundant protein in the body?
collagen
Type I collagen?
fibrous tissue (skin, tendon, ligament, bone)
Type II collagen?
hyaline and elastic cartilage
Type III collagen?
meshwork in liver and hematopoietic organs (reticular)
Type IV collagen?
basement membrane
Where is loose connective tissue found?
gut lamina propria, perivascular, surrounding glands, skin (Type II)
Where is dense regular CT found?
tendons and ligaments (Type I)
Where is dense irregular CT found?
covered by epithelium, skin, organ capsules (Type II)
Where is reticular CT found?
Lymphatic/hematopoietic organs (lymph nodes, thymus, spleen), lung, liver
Where is elastic CT found?
vessels, external ear, vocal chords, trachea, lung, skin
What is the function of elastic CT?
stretching, elastic recoil, resilience
Where is mucous CT found?
comb of chicken, turkey wattles, umbilical cord, subdermal - embryo
What is the function of fibroblasts/fibrocytes?
support, healing & repair, can produce: collagen, reticular fibers, elastic fibers, GAGs, proteoglycans, glycoproteins
What is the function of macrophages?
phagocytosis, normal tissue turnover, antigen-presenting cells
Where are macrophages found?
all tissues
What is the function of mast cells?
hypersensitivity
Where are mast cells found?
skin, respiratory, digestive
What is the function of plasma cells?
immunoglobulin production following specific antigen trigger (origin = lymphocyte)
What is the function of the extracellular matrix (ground substance)?
resist compression and stretch forces
What is ground substance composed of?
proteoglycans, glycosaminoglycans (GAGs), adhesive glycoproteins
What is the function of white fat?
energy storage, shock absorption, insulation/thermoregulation
What is the function of brown fat?
generate heat
Where is brown fat found?
limited distribution: axilla, perirenal, interscapular, mediastinum
