Conjunctiva/Cornea Flashcards

1
Q

Episcleritis

  • diffuse
  • nodular
A
  • young adults, recurring
  • benign, self-limiting, acute, unilateral, sectoral, mild pain
  • blanches with 10% phenyl

Causes:

  • idiopathic
  • collagen vascular disease (CRAP)
  • spirochetes (syphilis, Lyme)
  • virus
  • metabolic/gout
  • vasculitis
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2
Q

Scleritis

a) non-necrotizing
b) necrotizing
c) granulomatous

A
  • female 30-50 years old
  • severe boring pain to side of head/face

a) Non-Necrotizing:
- diffuse (least severe systemic) vs nodular (immobile)

b) Necrotizing:
- with inflammation: deadly, 33% die within a few years due to SEVERE autoimmune disease
- without inflammation: scleromalacia perforans - due to chronic RA, minimal injection, large patches of blue-grey thinning, lack of symptoms

c) Granulomatous:
RA > Wegener’s

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3
Q

Differentials for epiphora with mild to no pain.

A
  • blepharitis
  • ectropion
  • dry eye disease
  • nasolacrimal duct obstruction
  • conjunctivitis
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4
Q

Differentials for epiphora with moderate to severe pain.

A
  • corneal pathology
  • anterior uveitis
  • dacrycosystitis
  • entropion with trichiasis
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5
Q

Dacryocystitis

A
  • unilateral, painful, crusting, epiphora and occasional fever
  • below medial canthal tendon (if above, suspicious for lacrimal sac tumour)
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6
Q

Canaliculitis

A
  • unilateral, epiphora, mild tenderness, swollen puncta (“pouting puncta”)
  • mucopurulent discharge upon lacrimal sac expression
  • smoldering red eye
  • resistant to topical ophthalmic antibiotic

Caused by Actimoyces israelii

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7
Q

Most common cause of dacryocystitis

A
  • Staphylococcus aureus
  • Staphylococcus epidermis
  • Pseudomonas
  • Haemophilus influenzae in children
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8
Q

Jones I Test

A
  • checks patency of the nasolacrimal system
  • fluorescein on inferior fornix, drain in 5 minutes
Positive = patent nasolacrimal, fluorescein drains out
Negative = no draingage
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9
Q

Jones II Test

A
  • nasolacrimal irrigation with saline following negative test
  • reflex of saline from same canaliculus and punctum indicates blockage within canaliculus
  • reflex of saline from opposite canaliculus and punctum indicate nasolacrimal blockage
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10
Q

What condition gets “Trantas dots”? What is it?

A
  • collections of epithelial cells and eosinophils near the limbus
  • VKC
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11
Q

Causes of GPC

A

Immune mediated response:

  • protein deposits
  • mechanical trauma

Other causes:

  • blebs
  • prosthetics
  • scleral buckles
  • sutures
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12
Q

What is a giant papillae?

A

> 1mm in diameter; forms when neighbouring papillae break down septae and coalesce together after prolonged inflammation

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13
Q

Risks of GPC

A
  • EW hydrogel contact lenses
  • high water-ionic lenses
  • higher modulus of elasticity
  • poor replacement compliance
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14
Q

Ophthalmia neonatorum

A

Acute conjunctivitis within the first month of life. Can be caused by:

1) Gonoccocal - occurs within first 5 days
2) Chlamydia - 5 days - 2 weeks after.

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15
Q

What is “Bitot’s Spot”?

A

Keratin build-up in the epithelium due to Vitamin A deficiency and associated with dry eye.

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16
Q

Common associations for:

Acute, anterior, unilateral, non-granulomatous uveitis

A
  • Psoriatic arthritis
  • Ankylosing spondylitis
  • Inflammatory bowel disease
  • Reactive arthritis
    ^ also commonly HLA-B27 positive
  • Behcet’s disease
  • Glaucomatocyclitic crisis (Posner-Schlossman syndrome)
17
Q

Common associations for:

Chronic, anterior, non-granulomatous uveitis

A
  • Fuch’s heterochromic iridocylcitis (unilateral)

- Juvenile idiopathic iritis (JIA)

18
Q

Common associations for:

Chronic, anterior, granulomatous uveitis

A
  • Sarcoidosis
  • Tuberculosis
  • Lyme
  • Zoster/Simplex
  • Syphilis
19
Q

Causes of Peripheral Ulcerative Keratitis (PUK)

A
  • collagen vascular disease
  • rheumatoid arthritis
  • granulomatosis
  • SLE
  • GCA
  • relapsing polychondritis