Congenital Heart Defects: ASD/VSD Flashcards
ASD most commonly occur as defects in the
septum primum within the fossa ovalis (secundum ASD)
ASD can also occur
can involve the septum secundum near SVC (sinus venosus defects-less common)
cyanotic shunt
R -> L. worse for a kid
acyanotic shunt
L->R
Blood Flow is quantitated in terms of:
PULMONARY BLOOD FLOW (Qp)
SYSTEMIC BLOOD FLOW (Qs)
This gives us a ratio of Qp/Qs This will equal 1:1 (or 1) in a normal individual
The general rule is shunts that DO NOT cause increase in right heart size
(Qp:Qs
Ostium Secundum
most common
formed by failed growth of the septum secundum or
rapid reabsorption of the septum primum
OSTIUM SECUNDUM LOCATION
mid-atrial
PFO
A patent foramen ovale (PFO) is a small channel that has little hemodynamic consequence; it is a remnant of the fetal foramen ovale.
In some cases the PFO can be larger and require treatment
PFO closure from right side
The initial inflation of the lungs causes changes:
Decreases PVR results in increased blood flow from PA.
That increased amount of blood flows from the RA to the RV and into the PA’s and less blood flows through the foramen ovale to the left atrium.
PFO closure from right side
The initial inflation of the lungs causes changes:
Decreases PVR results in increased blood flow from PA.
That increased amount of blood flows from the RA to the RV and into the PA’s and less blood flows through the foramen ovale to the left atrium.
PFO closure due to left side
In addition, more blood returns from the lungs which increases the pressure in the LA.
The increased LA pressure and decreased right atrial pressure (due to pulmonary resistance) forces blood against the septum primum causing the foramen ovale to close.
This action functionally completes the separation of the heart into two pumps
ostium primum location
located low in the septum and can be considered a type of AV septal defect.
ostium primum sat.
could have normal sat. in upper atrium but higher in lower atrium
sinus venosus location and associated with
located high in the septum where the vena cava intersects with the right atrium, frequently associated with partial anomalous venous return (PAPVR)
May be inferior and/or superior
Cardiac Septation - review
Occurs at ______ and lasts
day 27 and lasts 10 days
At day ____ the paired atria fuse together to form a
common atrium.
27-28
clinically remarkable left-to-right shunt
ASD > 9MM
Any process that increases the pressure in the LV can
cause worsening of the left-to-right shunt. It also works on the right heart
IF ASD LEFT uncorrected
ressure in the right heart > left heart.
RA pressure > LA pressure
The pressure gradient reverses across the ASD the shunt will reverse
a right-to-left shunt (R->L) will now exist.
This shunt reversal phenomena is known as
Eisenmenger’s syndrome
Once right-to-left shunting occurs
oxygen-poor blood gets shunted to the left side of the heart.
This will cause signs of cyanosis.