Congenital Heart Defects Flashcards
What genetics problems can lead to heart defects?
Downs
Turners
Marfans
What is the term given to something that is harmful in pregnancy?
teratogen
What maternal infections affect foetal cardiac development?
Rubella
Toxoplasmosis
Lots more
How do we get right to left shunts?
Need a hole and an obstruction
Which shunt direction is cyanotic?
Right to left
How is a left to right shunt harmful if it acyanotic?
Pulmonary hypertension is harmful to lungs
List the cyanotic heart defects that involve shunts?
Atrio-Septal Defects
Ventriculo-Septal Defect
Patent Ductus Arteriosusm
What obstructive lesions in cardiac development can cause acyanotic defect?
Aotric stenosis
Pulmonary stenosis
Coarctation of the aorta (narrowing of the aorta at the level of the ligamentum arteriosum)
Mitral stenosis
What does the ductus arteriosum develop in to after birth?
Ligamentum arteriosum.
Is tetralogy of fallow cyanotic or not and why?
Cyanotic- 4 defects involving a hole and an obstruction. Over-riding aorta RVH Huge septal defect Pulmonary stenosis
Transposition of the great arteries is where the great vessels connect to the wrong side of the heart, does this cause cyanosis?
Yes- the right and left heart are no longer connected the right is only pumping systemically and the left is the only pulmonary circulation- so with no shunt we only have deoxygenated blood in systemic circulation
Why is a univentricular heart cyanotic?
Mixing ox deoxygenated blood an oxygenated blood entering the aorta for systemic circulation.
What is total anomalous pulmonary venous drainage?
The pulmonary trunk return to RA not LA. Left side of heart has no blood pumping at all- not compatible with life. Most exist with an Atrial Septal Defect as well.
What are the haemodynamic effects of an atrial septal defect?
L--> R shunt Increased pulmonary flow RV overloaded Pulmonary hypertension- rare Right sided heart failure Atrial arrhythmias may occur
Which chamber gets over loaded in a ventricular septal defect?
Left ventricle
R–>L shunt means the first ventricle to get the larger blood volume is the left.