CONFIRMED OSPE TOPICS Flashcards
list bacterial virulence factors
bacterial virulence factors = enable bacterial invasion and colonisation of periodontium
**bacteria characteristics
**- pili/fimbriae = adhesion/invasion
- capsule = protection against phagocytosis
- peptides = induces inflammation
**produced produced by bacteria **
- exotoxins = damage host immune cells
- enzymes = damage host proteins + acquire nutrients
OUTLINE THE TYPES OF DENTINE
primary
secondary
tertiary
describe primary dentine
- formed BEFORE to eruption - deposited at DEJ
- has incremental lines
- outer layer = mantle dentine [150um thick]
outer layer is divided into: [from outside to in]
- circumpulpal dentine
- globular dentine
- peritubular/intratubular dentine
- intERtubular dentine
describe secondary dentine
- formed AFTER completion of root formation and thoroughout tooth ageing process
- aka circumpulpal dentine
- scatters more slowly than primary
- causes canals to be smaller w age [deposition = decreased pulp chamber size]- - forms at roof and floor of roof chamber
describe tertiary dentine
forms if dentine experiences
- mechanical trauma
- irritation
- exposed hypersens dentin
- carious dentine
- traumatic cavity prep
reactionary
- forms in response to insult, damange sustained but **existing cells recover **
- formed by existing odontoblasts
reparative
- forms in response to insult, damage sustained –> original odontoblasts destroyed –> induces odontoblast precursors to differentiate and produce calcified tissue
describe general dentin properties
- forms BULK of tooth
- covered by enamel in the crown and cementum in the root
- consist of large number of small parallel tubules in mineralised collagen matrix [contains odontoblastic processes and dentinal fluids]
- harder than bone and cementum but softer than enamel
- by weight [inorganic 70%, organic 20%, water 10%]
outline the layers of dentine
crown
- mantle dentine
- interglobular dentin
- circumpulpal dentine [bulk] - covers pulpal space
[circumpulpal further div into:
- globular dentine
- peritubular/intratubular dentine
- intERtubular dentine
root
- hyaline layer
- granular layer of Tomes
- circumpulpal dentin [bulk]
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briefly describe mantle dentine
deposited FIRST under DEJ in 150um wide band - mineralised by matrix vesicles
fibres perpendicular to DEJ
secreted by immature odontoblasts
briefly describe circumpulpal dentine
layer of dentine around outer pulpal wall - makes bulk of dentin in both crown + root
formed and matured after mantle dentine
briefly describe inter/globular dentine
between mantle and circumpulpal
beneath mantle dentine [crown] and grnular layer of tomes [root]
calcified following formation of matrix
becomes larger –> fuses as dentine develops - interglobular spaces present
briefly describe peritubular and intertubular dentin
peritubular dentin
- immediately surrounds dentinal tubule
- higher mineral content and LACKS collagenous matrix [more calcified and mineralised - less organic structure]
intertubular
- forms bulk of dentine around dentinal tubules of crown and root
- less mineralised
describe PDL
fibrous collagen CT between alveolar process and cementum
occupies periodontal space
contains
- fibroblasts, osteoblasts, cementoblasts
- blood cells
ground substance - 70% water w glycoproteins and proteoglycans
highly vasculuar + nerves
provides attachment of cementum to surrounding alveolar bone keeping the teeth resting in its socket - - acts as suspensory ligaments of teeth
- major func = permits tooth to withstand force of mastication
outline PDL organisation
group according to location
- gingival group
- around necks of tooth - support gingiva
- 1 alveologongival [free]
- 2 dentogingival [attached]
- 3 circular / circumferential fibres
- 4 dentalperiosteal - transeptal
- in between teeth
- cementum to cementum over alveolar crest
[func = resist rotational forces - holds teeth in interproximal contact] - dentoalveolar
- cementum to bone
- contains
alveolar crest group = resist tilting/rotation
horizontal group = resist tilting M/D/L/F / rotation
oblique group = resist inwards pushing and rotation
apical group = resist outward pull and rotation
interradicular group
outline oral mucosa classifications
lining mucosa
- found in areas which dont func in mastication
- softer surface texture, moist surface, ability to stretch/compress, cushions underlying structures
- eg soft palate, central surface of tongue, floor of mouth, alveolar mucosa, labial and bicca; mucosa
masticatory mucosa
- comes into primary contact w food during mastication
- covers immobile structures and firmly bound - well adapted to withstanding abrasion
- eg hard palate, free + attached gingiva
specialised mucosa
- assists in mastication + taste buds
lingual papillae
- foliate papillae - not well devel in humans
- filiform - ant 2/3 tongue
- fungiform - ant 2/3 tongue
- circumvalate - adjc//ant to terminalis sulcus
briefly describe the lamina propria
CT supporting oral epithelium
high vascularised capillary networks/loops
composed of TWO layers
1. papillary layer
- most superficial
- associated w rete ridges, collagen fibres and capillary loops
- reticular layer
- deeper layer
- dense conc of collagen arranged into bundles lying parallel to surface plane
list the layers of lining mucosa from superficial to deep
- superficial layer [flattened cells]
- intermediate layer
- basal layer [cuboidal above lamina propria]
- lamina propria [capillary loops + parallel bundles]
- submucosa
- muscle
list the layers of masticatory mucosa from superficial to deep
- keratin layer
- granular layer
- prockle layer
- basal layer [cuboidal cells above lamina propria]
- lamina propria [capillary loops + parallel bundles]
- minimal or absent submucosa
- bone