Conditions

Question 1

What are the symptoms and signs of Polycystic Ovary Syndrome?

Answer 1

• Excess Androgens
  
  • Hirsutism (Clinical)
  • Testosterone Levels (Biochemical)
• Infrequent Periods (Anovulation)
• Polycystic Ovaries
  
  • Diagnosed through ultrasound

Question 2

What is the pathology shown in this ovarian ultrasound?

Answer 2

Polycystic Ovary

Question 3

How can we induce ovulation?

Answer 3

• Clomifene
• Gonadotrophins

Question 4

How does clomifene induce ovulation?

Answer 4

Blocks eostrogen receptors in anterior pituitary.

This leads to increased FSH production as a feedback loop reponse.

Question 5

What is the biggest downside of using gonadotrophin for ovulation induction?

Answer 5

It is a multifollicular recruitment:

• Risk of multiple pregnancies
• Risk of Ovarian Hyperstimulation

This is why monitoring scans are advised for every gonadotrophin OI cycle.