Concepts Flashcards
Measures H ion concentration
PH
pH levels are _______ to H concentration
Inversely proportional
Acidosis: ____ ph, _____ H ions
Decrease, increase
Alkalosis: ____ ph, _____ H ions
Increase, decrease
Acids: ______ H ions in solution
Release
Bases: _______ H ions in solution
Retain/accept
Acid that can be eliminated in the body as gas
Volatile Acid
Only volatile acid produced in the body
Carbonic Acid (H2CO3)
Carbonic Acid dissociates into ______ and _____
Carbon dioxide, water
CO2 is eliminated from the body through?
Lungs
Acids that is produced in the body that is metabolized or excreted from body in fluid
Nonvolatile Acid
Examples of Non volatile acid (LaHaPaSa)
Lactic Acid
Hydrochloric Acid
Phosphoric Acid
Sulfuric Acid
Substances that prevent major change in pH by removing or releasing H ions
Buffers
When excess acid is present in body fluid, they _________ to minimize change in pH
Bind with H ions
If body fluids become too basic or alkaline, they _____________, restoring pH
Release H ions
Major Buffer Systems
a. Carbonic-Acid Bicarbonate Buffer system
b. Phosphate Buffer System
c. Protein Buffer System
A weak base
Bicarbonate
When an acid is added to the system, the H ion in the acid _______ with ______ and pH changes ______
Combines, Bicarbonate, slightly
A weak acid
Carbonic Acid
If a base is added to the system it _______ with __________ and pH ___________
combines, carbonic acid, normal range
Normal Ratio of Bicarbonate and Carbonic Acid
20 part bicarbonate; 1 part carbonic acid
Normal Ratio of Bicarbonate to Carbonic Acid
20 parts bicarbonate; 1 part carbonic acid
Addition of a strong acid to ECF depletes _______, causes pH to drop known as ______
Bicarbonate, Acidosis
Addition of a strong base depletes ______ causes the pH to rise known as _______
Carbonic Acid, Alkalosis
Contribute to buffering for organic acids produced by cellular metabolism
Intracellular and plasma proteins (serum albumin)
In RBCs, ______ acts as a buffer for H ion
Hemoglobin
Also serve as extracellular buffers, helping to maintain a stable pH
Inorganic phosphates
A potential acid
Carbon dioxide
What is stimulated in the brain when there is an acute increase in either CO2 or H ions in the blood?
Respiratory center
What is the respiratory center of the brain?
Medulla oblongata
Increased rate and depth of respirayon
Hypercapnea
It depresses the respiratory center
Morphine Sulfate
Where are the excess nonvolatile acids produced during metabolism eliminated?
Kidneys
In acidosis, kidneys _______ H ions and _____ bicarbonate
Excrete, retain
In alkalosis, kidneys ______ H ions and _____ bicarbonate
Retain, excrete