Conception, Fetal Development & Genetics Flashcards

(43 cards)

1
Q

How long is a mentrual cycle and when does ovulation occur

A

Mentraul cycle is 28 days

Ovulation occurs 14 days prior to menses (bleeding)

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2
Q

Signs of ovulation

A

Increase basal body temperature

Pain over ovary

Cervical mucus becomes clear, slippery, stretchy

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3
Q

Once ovulation occurs how long is ovum and sperm viable

A

Ovum is viable for 24 hrs

Sperm 48-72hrs

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4
Q

Where does fertilization occur usually

A

Outer third portion of fallopian tube

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5
Q

Zygot ( resulting structure) produces what and helps with what

A

Produces HCG which helps maintain the corpus luteum until implantation

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6
Q

What is the corpus luteum?

A

Where the ovum is release from in the ovary

Produces estrogen and progesterone to prepare endometrium for implantation

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7
Q

Implantation of trophoblast (outer cell of zygot) occurs when and where

What it produces

A

7-10 days upper posterior uterus

Produces HCG until placenta fully functioning

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8
Q

Dizygotic

A

Fraternal

Two ovum
Two sperm
Two zygotes

Have 2 amnions
Have 2 chorions

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9
Q

Monozygotic

A

Identical
One fertilized ovum splits (DNA splits)

May have:
Mono/mono (share placenta and sack)
Mono/di (own sack share a placenta)
Di/di (own sack and placenta)

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10
Q

Stages of fetal development

A

Zygotic stage
Blastocyst stage
Embryonic stage
Fetal stage

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11
Q

Zygotic stage

A

Fertilization of sperm and egg (conception)

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12
Q

Blastocyst stage

A

Zygote divides into a solid ball of cells and attaches to the uterus

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13
Q

Embryonic stage

A

End of the 2nd week thru eighth week

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14
Q

Fetal stage

A

Differentiation and structures specialized by end of the eighth week until birth

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15
Q

Once impanted called a what
After 8 weeks becomes what
What is most risk from in embryonic stage
What happens end of 8th week
Fetal period

A

Once impanted called embryo
After week 8 called fetus
Most risk from teratogens

End of 8th week organ systems are present and refinement of systems occurs

Fetal:9-40wks

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16
Q

40 week gestation break down

A

Gestation starts on 1st dat of last menstrual cycle
3 trimesters of 13 weeks
Trimesters:
1: 0-12 weeks
2: 13-27 weeks
3: 28-40 weeks

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17
Q

Chorion

A

Outermost layer

Fingers called chorionic villi which assist in attaching and implanting into uterus. Gives way to the placenta

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18
Q

Amnion

A

Fuses with chorion to become amniotic sac

Inner protective membrane contains the embryo and amniotic fluid

19
Q

Amniotic fluid
At term
Polyhydramnios
Oligohydramnios

A

At term: 700-1000ml

Poly: >2000ml (caused by GI problems)

Oligohydramnios <500ml (caused by renal, poor placental perfusion)

20
Q

Amniotic fluid functions (6)

A

Cushion/ shield against pressure
Control temp
Allow for symmetrical growth & development
MSK development
Protect against cord compression
Keep membranes from adhering to fetal parts

21
Q

Placenta
Functioning by when
Amount of layers of cells between mom/fetal circulation
Provides what exchange
Immunologic properties
Why is it an endocrine gland?

A

By 3rd week
One layer (so their blood never mixes)
Metabolic and nutrient exchange
IP: prevents rejection of new genetic material
Produces hormones from pregnancy

22
Q

Placenta as endocrine gland: what hormones

A

HCG
Estrogen
Progesterone
Prolactin
Human placental lactogen
Relaxin

23
Q

Placenta: HCG

Present where and when’
Max amount at how many days vs lowest
Stays high until when

A

Present in serum(blood) 8-10 days after fertilization
Present in urine at missed menses
Amount:
Max 50-70 days then declines to lowest 100-130 days

Stays high until placenta is fully functioning and produces its own estrogen and progesterone

24
Q

Placenta: estrogen

A

Growth in uterus, breast
Increased vascularity, and vasodilation

25
Placenta: progesterone
Nutritive for blastocyst Development of endometrium for implantation Decreases contractility of uterus
26
Placenta: prolactin
Important role in lactation
27
Human placental lactogen Stimulates changes in what Can cause what
Stimulates changes in maternal metabolism Can cause insulin resistance leading to gestational DM
28
Placenta: relaxin
Softens ligaments and cartilage in skeletal muscles Quiets the myometrium (prevents it from contracting during pregnancy0
29
Placenta name for baby side vs mom side
Baby: shiney shultz Mom: dirty dunken
30
Umbilical cord Connects what Contains what vessels Insertion of cord should be what Check cord at birth for vessels Check for what
Connects embryo/fetus to placenta Contains 1 large vein and 2 small arteries (AVA) Cord should be center of the placenta Check for nuchal cord (around neck) Check for knots (might have nots in cord)
31
Fetal circulation (know where)
Placenta One umbilical vein (oxygenated blood) Ductus venosus Foramen ovale (between atrium) Ductus arteriosus Two umbilical arteries (unoxygenated blood)
32
Pulmonary pressure is what vs systemic pressure
Pulmonary pressure is high Systemic pressures low This is why the blood shunts thru foramen ovale and skips the ventricles and lungs In case where it goes to ventricles it will shunt thru ductus arteriosus in the pulmonary artery.
33
Milestones in fetal development 8-12wks 20wks 22wks 28wks 32wks 36wks
8-12: FHR with doppler 20: quickening (movement) sooner with multiple pregnancy 22: earliest point of viability (production of surfactant) 28: more developed respiratory system 32: sucking reflex 38: survival with little support
34
Lung maturation (surfactant) When its produced What happens when further in gestation What does it do
22 wks surfactant is starting to be produced Further in gestation more surfactant is produced Surfactant prevents alveoli from sticking together by reducing surface tension and coats the alveoli
35
Toxoplasmosis
Teach avoid raw/rare meat and cat litter Cause: blindness, cognitive impairment
36
Chromosomal abnormalities do not follow what?
Patterns of inheritance
37
AFP alpha-fetoprotein Indicates
Neural tube defects Down syndrome
38
Amniocentesis
Drawl out amniotic fluid
39
Chorionic villi sampling
Thru vaginal or abd drawl fluid
40
Fetal nuchal translucency What is Indication
Ultra sound Trisomies (including downs syndrome)
41
Cell-free fetal DNA What it is Indication
Draw moms blood Tells us: Fetal sex Some trisomies
42
FSH (follicular secreting hormone)
Bleeding Days: 1-14 Primary/secondary/graafian follicle
43
LH (luteal hormone)
Days: 14-28 Imature follicle released to fallopian tube Ovulation and corpus luteum