COMQUEST material updated Flashcards
Initial test for diagnosing acromegaly
Insulin-like growth factor level (get an MRI)
Collection of blood beneath the periosteum of one of the calvarial bones; does not cross the suture lines
Cephalhematoma
Egg-on-a-string x-ray
Transposition of the great vessels
Benign tumors most commonly seen in women of reproductive age and are associated with contraceptive use, anabolic steroids, and glycogen storage disease
Hepatic adenomas (surgically remove if they are symptomatic, more than 5 cm, or do not regress after discontinuation of OCPs)
Mononeuritis multiplex and hepatitis B are associated with
Polyarteritis nodosa
Chest pain precipitated by hot or cold liquids without other obvious pathology is most likely the result of
diffuse esophageal spasm (use manometry to diagnose)
Classic triad of patent ductus arteriosus, deafness, and cataracts
Rubella (German measles)
Hypocellular marrow with loss of precursor cells, predominated by fat and stroma, is diagnostic of
aplastic anemia
Which labs should be checked prior to prescribing lithium?
BUN/Cr, thyroid function, and pregnancy
Most common causative agent of osteomyelitis
Staph aureus
Elevated methylmalonic acid and homocysteine
Vitamin B12 deficiency
Splitting of the basement membrane (tram-track appearance)
Membranoproliferative glomerulonephritis
Bead-like pattern on cholangiography; presents with pruritis and jaundice
Primary sclerosing cholangitis (associated with ulcerative colitis)
Boot-shaped heart
Tetralogy of Fallot
Low risk moms are advised to take how much folic acid before conception?
.4 mg (400 mcg)
Painful limp after a URI
transient synovitis
Cafe-au-lait spots, neurofibromas, freckling of the groin or the axilla, skeletal abnormalities, ad hamartomas of iris (Lisch nodules)
Neurofibromatosis type 1 (more common)
Always start lymphatic drainage techniques with
thoracic inlet release
Sacrum nutation and counternutation, while standing,occur about the
middle transverse axis
Defect in excretion of bilirubin and results in conjugated hyperbilirubinemia; liver has black pigmentation on biopsy
Dubin-Johnson syndrome
What is the most sensitive screening test for SLE?
ANA
Transient hyperthyroidism and thyroid tenderness followed by hypothyroidism
Subacute thyroiditis (de Quervain thyroiditis)
Positive blood culture for S. bovis along with features of infective endocarditis, you should suspect
colorectal cancer (order a scope)
Lateral and posterior margin of the IT band (Chapman’s point)
Prostate
Once the anterior fontanelle is closed, it is known as
bregma
Best test to assess iron deficiency
Ferritin
Once the posterior fontanelle is closed, it is known as
lambda
Hypogonadism plus impaired sense of smell equals
Kallmann syndrome
What leads to insulin resistance during pregnancy?
Human placental lactogen (chorionic somatomammotropin)
Hand, foot and mouth disease is most commonly caused by
Coxsackie A virus
Which type of stroke will result in contralateral motor and sensory deficit of the face, hand and arm?
Middle cerebral artery stroke
Gastric ulcers are more common in which blood type?
Type A
gAstric ulcers = type A
First-line vasopressor for sepsis
Norepinephrine
Decreased iron (Fe), decreased ferritin, increased TIBC
Iron deficiency anemia
The most common cause of SBO in adults in the US is
adhesions
The presence of a widened mediastinum on chest x-ray in patients who handle animal wool/hides/hair is a classic finding of
inhalational anthrax
Patients have a higher incidence of colon and multiple other cancers, especially endometrial cancer in women
Hereditary non-polyposis colorectal cancer (Lynch syndrome)..mutation of DNA mismatch repair genes. 3-2-1 rule: three affected family members, involving at least two generations, one or more cancer diagnosed before the age of 50
Hematochezia and narrow (pencil-thin) stool is usually indicative of
Left-sided colon cancer
Anytime a pt presents with a new onset murmur, what is the diagnostic modality of choice?
Echocardiogram
First-line tx to slow diabetic nephropathy
ACE inhibitors
Antimitochondrial antibodies are associated with
primary biliary cirrhosis
Pruritus associated with primary biliary cirrhosis (antimitochondrial antibodies) can be treated with
cholestyramine or colestipol
Tumor marker that is useful in the management of pancreatic cancer
CA 19-9
The inherent motion of the sacrum between the ilia as part of the primary respiratory mechanism happens on the
superior transverse axis (respiratory axis)
Tumors that arise at the confluence of the hepatic ducts
Klatskin tumors
Drugs of choice for absence seizures
Valproic acid or ethosuximide
Most common form of leukemia in children
Acute lymphoblastic leukemia (ALL) TdT+
Overdose associated with nystagmus
PCP
What is the most common infection leading to GBS?
Campylobacter jejuni
When the forearm pronates, the radial head moves
posterior
Patient’s limit for range of motion
Physiologic
Most specific test for myasthenia gravis
Acetylcholine receptor antibody test
Osteomyelitis in a patient with sickle cell disease is most likely due to
Salmonella
Most common cause of nephrotic syndrome in children
Minimal change disease (effacement of foot processes)
Seizures, mental retardation, ash-leaf spots (hypomelanotic macules), facial angiofibromas, and cutaneous nevi
Tuberous sclerosis
Treatment of choice for Shigella dysentery
Ciprofloxacin, azithromycin, or ceftriaxone
Essential tremor is best treated with
beta blockers
Smudge cells are a characteristic finding in
chronic lymphocytic leukemia
In a neutral group of segments, sidebending and rotation occur in
opposite directions
Leukocytosis after an infection with a lab finding of increased leukocyte alkaline phosphatase
Leukemoid reaction
Similar to Dubin-Johnson syndrome, resulting in conjugated hyperbilirubinemia, but the liver will not turn black
Rotor syndrome
Turner syndrome is treated with
human growth hormone and estrogen replacement therapy
Muscles involved with correction of a first rib dysfunction
Anterior and middle scalenes
Side effect associated with trazodone
Priapism
Most useful lab value to monitor heparin therapy
PTT
Best initial choice in workup of a breast mass in a woman < 30 years old or pregnant
Breast ultrasound
Most preferred test to diagnose renal cell carcinoma
CT with and without contrast
Patient presents with hundreds of thousands of adenomatous polyps in addition to osteomas, dental abnormalities, desmoid tumors, and cutaneous lesions
Gardner’s syndrome
Antidepressants associated with strong anticholinergic effects (dry mouth, drowsiness, nausea, constipation)
Tricyclic antidepressants
Multiple pigmented spots most often found on the lips, oral mucosas, and GI mucosa
Peutz-Jeghers syndrome
Most infantile hemangiomas require
observation
In dorsiflexion, the talus is
posterior
Zenker’s diverticulum is managed with
myotomy +/- diverticulectomy
First time PE should be treated with heparin followed by coumadin for
3-6 months
Causes ipsilateral hemiparesis, loss of proprioception and vibratory sense, as well as contralateral loss of pain and temp
Brown-Sequard syndrome
When endocarditis is suspected, the most important initial step is to
obtain three sets of blood cultures
Most common cause of meningitis from newborn to 3 months
GBS
Arousal by the clothing worn by the opposite sex
Transvestic fetishism
Most common inherited thrombophilia
Factor V Leiden
Injury of which nerve causes winging of the scapula?
Long thoracic nerve (serratus anterior)
Most common cardiac manifestation associated with Marfan’s syndrome
Mitral valve prolapse
Viscerosomatic reflex of the thyroid gland is between
T1-T4
Polycythemia vera leads to _______ erythropoeiten
decreased
Highest diagnostic sensitivity for the diagnosis of colorectal cancer
CEA (carcinoembryonic antigen)
Appropriate first-line tx for uterine relaxation for retained placenta
Nitroglycerin
The middle meningeal artery can be found just deep to
pterion
Most common type of testicular germ cell tumor
Seminomas (bhCG might be elevated)
First line tx for sideroblastic anemia with ringed sideroblasts
Pyridoxine (Vit B6)
Most common cause of meningitis from 3 months to 9 years
S. pneumoniae
Test of choice for suspected nephrolithiasis
Noncontrast CT
In plantarflexion, the talus is
anterior
Pruritic, purple, polygonal, papules/plaques
Lichen planus (look for Wickham striae)Most common: flexor surfaces of wrists/ankles