Compounding Lab Midterm 2

Question 1

Witepsol

Answer 1

suppository base

Question 2

cocoa butter

Answer 2

suppository base

Question 3

water

Answer 3

emulsifier

cosolvent

Question 4

PEG

Answer 4

suppository base (higher number polymer takes longer to melt than the lower number polymer)

Question 5

cetyl esters wax

Answer 5

emulsifier

emollient (oil phase)

Question 6

yellow wax

Answer 6

base
stiffening agent (oil phase)

Question 7

mineral oil

Answer 7

base

emollient (oil phase)

Question 8

sodium borate

Answer 8

emulsifier

preservative (water phase)

Question 9

dimethicone

Answer 9

anti-foam emulsifier (oil phase)

Question 10

cetyl alcohol

Answer 10

emulsifier

emollient (oil phase)

Question 11

petrolatum

Answer 11

base

emollient (oil phase)

Question 12

stearic acid

Answer 12

emulsifying agent (oil phase)

Question 13

propyl paraben

Answer 13

preservative (oil phase)

Question 14

glycerin

Answer 14

humectant (water phase)

Question 15

TEA

Answer 15

pH adjuster (water phase)

Question 16

Mg Al Silicate

Answer 16

emulsifying/stabilizing agent (water phase)

Question 17

methyl paraben

Answer 17

preservative (water phase)

Question 18

water

Answer 18

solvent

bulking agent

Question 19

white wax

Answer 19

stiffening agent

Question 20

lanolin

Answer 20

ointment base

emollient

Question 21

sweet almond oil

Answer 21

emollient

Question 22

ethanol

Answer 22

cosolvent

Question 23

glycerin

Answer 23

co solvent

Question 24

white petrolatum

Answer 24

base

Question 25

mineral oil

Answer 25

levigating agent

Question 26

spermaceti

Answer 26

emollient

Question 27

liquid petrolatum

Answer 27

oleaginous vehicle

Question 28

What aux labels go on suppositories?

Answer 28

rectal use only
refrigerate
may cause dizziness/drowsiness

Question 29

What aux labels go on hand creams?

Answer 29

for external use only

Question 30

What aux labels go on lotion?

Answer 30

for external use only

Question 31

What aux labels go on nail treatment?

Answer 31

for external use only

Question 32

What aux labels go on nasal spray?

Answer 32

for the nose
do not take by mouth
may cause dizziness/drowsiness

Question 33

What aux labels go on HC ointment?

Answer 33

for external use only

Question 34

What aux labels go on lip balm?

Answer 34

for external use only

Question 35

Generally detail the steps for making a suppository.

Answer 35

melt the suppository base (target temp is less than 55 dC)
disperse API in liquid base
pour into molds
cool in ice bath
clamp melt tops

Question 36

Generally detail the steps for creams and lotions.

Answer 36

melt the oil phase together
melt the water phase together
add the water to oil phase (when two phases are within 5 dC of each out between 65-70dC)
mix
cool

Question 37

Generally detail the steps for nasal spray.

Answer 37

mix ethanol, MP, glycerin, drug in a beaker
add water to qs
filter and dispense
weigh and calculate DDV to put on label after sig

Question 38

Generally detail the steps for nail treatment.

Answer 38

heat and melt ingredients together to 55dC
stir
dispense

Question 39

Generally detail the steps for HC ointment.

Answer 39

levigate powder using agent
add preservative and petrolatum
mix

Question 40

Generally detail the steps for lip balm.

Answer 40

mix everything together
melt
pour into the tube and cool
over fill, surface tension will prevent spill