Compounding Flashcards

1
Q

what are compounding facilities besides hospitals and pharmacies (5)

A

veterinary clinics, cancer centers, sports medicine clinics, research clinics, holistic centers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what kinds of medications are compounded? (7)

A

oncologic, radiopharmaceutical, ophthalmologic, podiatric, neurologic medications & vitamins/supplements

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what is non-sterile compounding? it is in accordance with the ___.

A

compounding 2 or more ingredients in accordance with the US pharmacopeial convention (USP) chapter 795

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

compounding is necessary when ___ (3)

A

-need specialized dosage strengths
-when product commercially unavailable
-product flavoring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what technique must a PT use to ensure purity standards when compounding? What does it involve? (4)

A

aseptic technique - sterile work area, good hygiene, sterile handling, contaminate-free solutions/reagents

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

non-sterile compounding is also called

A

extemporaneous compounding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what can non-sterile compounding make? (9)

A

ointment, cream, paste, oil in water emulsion, solution, lotion, capsule, tablet, suppository

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

formulas for non sterile compounding of frequent prescriptions can be found in the

A

master formula record

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

true or false

compounded medications must be verified by the pharmacist

A

true

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

what is included in a non-sterile compounding log (7)

A

name of product, lot #, date made, expiration/beyond use dates, quantity, amount of ingredient used, PT/pharmacist initials

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what is USP chapter 795

A

standard for non-sterile compounding for purity, quality, and strength

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

tituration

A

reduce to fine powder by grinding

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

a ___ can be made using a mold

A

tablet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what is sterile compounding

A

using sterile or non sterile product to create sterile product for intravenous or parenteral use

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what is USP chapter 797? What does it involve? (3)

A

the guideline that sets sterile compounding measures - clean environments such as air quality (to avoid contamination), training of personnel/continuing education, and stability/sterilization techniques

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

routes of administration for:
non-sterile compounding (3)
sterile compounding (2)

A

non = oral, rectal, topical
sterile = intravenous & parenteral

17
Q

what does parenteral mean

A

injection/infusion subcutaneously, intravenously, or intramuscularly

18
Q

what is used for infection control (5)

A

hand hygiene, vaccination, education, TB testing, PPE/gowning

19
Q

what is PPE when gowning up (6)

A

lab coats/suits, shoe covers, masks, gloves, goggles, bouffant caps

20
Q

what is the order of garbing up (5)

A

dirtiest to cleanest
shoe covers/cap, wash hands, gown/masks, enter room & cleanse hands with alcohol sol, gloves

21
Q

what is the anteroom and clean room

A

anteroom = where preparation takes place (such as garbing up) to enter clean room = room free from contaminants

22
Q

what happens in the anteroom (5)

A

label prep, order entry, garbing up, storage area, wash hands

23
Q

___ water is used to dilute/dissolve medications, ___ water is used for irrigation only

A

bacteriostatic, sterile water

24
Q

the strength of isopropyl alcohol required for disinfecting the pharmacy

A

70%

25
Q

Which one is isotonic (2) & hypotonic (1)
What is used for (if time)

normal saline (NS) 0.9%
dextrose 5%
D5NS
0.45% normal saline (1/2 NS)
lactated ringers soltion
IVPB
potassium chloride 10, 20, 40 MEQ solution

A

NS = NaCl, isotonic used for fluid replacement & irrigation wounds
D5 = fluid replacement & caloric supply
D5NS = fluid/electrolyte replacement & caloric supply used for IVs
1/2 NS = hypotonic, fluid/electrolyte replacement for IVs
ringers = isotonic IV fluid/electrolyte replacement
potassium = treatment potassium deficiencies

26
Q

what can cause chemical degradation of sterile compounds? (4)

A

time, pH, drug structure, temperature

27
Q

what are factors that affect sterile compounding so they are no longer potent (4)

A

-chemical degradation
-order of addition
-drug precipitation
-photo degradation (light) due to oxidation/reduction

28
Q

in the USP 797 for sterile compounding, what do each risk level cover? (1, 2, 3)

A

1 - all medications & procedures
2 - bulk compounding (multiple CSP for several patients or multiple CSPs for one patient
3 - covers all requirements for 1 & 2, those susceptible to contamination

29
Q

what is infusion and flow rate when preparing IV sterile compounds

A

infusion = dosing rate
flow rate = drops per minute/hr

30
Q

what is included in a sterile compounding label (11)

A

patient name, identification number, hospital room, IV solution & volume, medication, strength, instructions, initials, auxiliary labels, beyond use date (expiration date)

31
Q

How often should the weights on a Class A balance be calibrated?

A

annually