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IMMUNOHEMATOLOGY AND BLOOD BANKING > COMPONENT PREPARATION > Flashcards

COMPONENT PREPARATION Flashcards

1
Q

Collecting whole blood and transforming it into components uses what type of method

A

Centrifugation

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2
Q

a mechanical devices that apply pressure to the blood bag, which allows blood components to flow from one bag to another

A

Plasma expressor

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3
Q

quality of each scales using calibrated standard weights should be performed periodically to ensure that the scale is performing within specification

A

scales

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4
Q

the tubing that connect blood bag is usually made of

A

(PVC) Polyvinyl chloride

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5
Q

it uses a combination of targeted radio frequency energy and pressure to melt and seal the tubing

A

Tube sealers

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6
Q

allows two separate blood bag to be connected via their PVC tubing without breaching the integrity of either container

A

Sterile connection device

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7
Q

Uses to freeze plasma, liquid components may be placed in a standard -18 degree C or colder freezer

A

Plasma freezer

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8
Q

storage devices include:

A

refrigerators
freezers
platelet agitators

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9
Q

how many anticoagulant -preservative for every 100 mL of whole blood targeted for collection

A

14mL

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10
Q

whole blood must be stored at what temperature

A

1-6 C

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11
Q

Quality control indicator for this component are NOT routinely measure

A

Whole blood

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12
Q

red blood cells is separated from whole blood by what methods

A

Centrifugation
Apheresis
Sedimentation (less commonly)

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13
Q

AS (additive solution ) must be added to the RBC component within how many days

A

3 days

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14
Q

RBC WITH additive solution, resulting in a finished product with a hematocrit of

A

55% to 65%

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15
Q

RBC WITHOUT additive solution must have a finished hematocrit of

A

65% to 80%

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16
Q

this component must be drawn by a single nontraumatic venipuncture and the concentrate must be prepared within 8 hrs of collection

A

Platelet

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17
Q

Platelets derived from whole blood

A

Random Donor Platelet (RDP)

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18
Q

Platelet product obtain from apheresis donation

A

Single Donor Platelet (SDP)

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19
Q

how to store platelet concentration

A

Room temp
20-24 C with constant agitation

20
Q

RDP should contain how many platelets

A

5.0 x 10^10 platelets

21
Q

SDP should contain at least how many platelets

A

3.0 x 10^11 platelets

22
Q

it is the removal of white blood cell from blood or blood components prior to transfusion

A

Leukocyte reduction or leukoreduction

23
Q

SDP should only contain how many residual white blood cells

A

5.0 x 10^6 residual white blood cells

24
Q

RDP should only contain how many residual white blood cells

A

8.3 x 10^3 residual white blood cells

25
Q

at least how many percent of the original component must be recovered after leukoreduction

A

85%

26
Q

it protects against transmission of CMV to patients at increased risk of CMV disease

A

leukoreduction

27
Q

frozen within 8 hours

A

FFP - fresh frozen plasma

28
Q

frozen within 24 hrs

A

PF24- plasma frozen within 24 hrs

29
Q

FFP and PF24 can be stored for 1 years at what temp

A

-18C

30
Q

FFP & PF24 can be stored for 7 yrs at what temp

A

-65 C

31
Q

thawed temperature

A

30 - 37 C

32
Q

FFP can be manufactured into

A

cryoprecipitate and cryo-poor plasma

33
Q

What is the volume of FFP or PF24 from apheresis

A

as much as 800mL

34
Q

what is the volume of a unit of FFP or PF24 from whole blood

A

200-375 mL

35
Q

most often used for transfusion or plasma exchange in patients with thrombotic thrombocytopenia purpura

A

CPP - cryo-poor plasma

36
Q

cryoprecipitate pooled in the transfusion service laboratory using an open system must be transfused with how many hours

A

4hrs

37
Q

FDA and AABB recommended a minimum dose of gramma irradiation of ____ to the central portion of the blood unit

A

25Y

38
Q

irradiation may be achieved by using what radioactive sources

A

cesium-137
cobalt-60
x-ray

39
Q

it is often transfused during the neonatal period or in infants younger than 4 months of age due to their small blood volume

A

aliquoted blood products

40
Q

it allows multiple blood components to be transfused at a single event

A

pooled components

41
Q

T/F
multiple units of red blood cells are NOT typically pooled together, but ither product types may be pooled

A

TRUE

42
Q

platelets pooled in an open systems must be transfused within how many hrs

A

4rhs of pooling

43
Q

it is stored for up to 10 yrs for those patients with rare phenotypes, for autologous use

A

frozen, deglycerolized RBCs

44
Q

-most widely used
-increases the cryoprotective power of the glycerol, thus allowing slow, uncontrolled freezing process
-provides storage at -65 C or below

A

high glycerol (40% weight per volume)

45
Q

Cryoprotection of the glycerol in minimal, and a very rapid, more controlled freezing procedure is require
-liquid nitrogen is routinely used for this method

A

Low glycerol (20% weight per volume)

46
Q

used to treat patients with hemophilia A and have almost completely replaced cryoprecipitate as the product of choice

A

Factor VIII concentrates

IMMUNOHEMATOLOGY AND BLOOD BANKING (3 decks)

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