COMPONENT PREPARATION Flashcards

1
Q

Collecting whole blood and transforming it into components uses what type of method

A

Centrifugation

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2
Q

a mechanical devices that apply pressure to the blood bag, which allows blood components to flow from one bag to another

A

Plasma expressor

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3
Q

quality of each scales using calibrated standard weights should be performed periodically to ensure that the scale is performing within specification

A

scales

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4
Q

the tubing that connect blood bag is usually made of

A

(PVC) Polyvinyl chloride

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5
Q

it uses a combination of targeted radio frequency energy and pressure to melt and seal the tubing

A

Tube sealers

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6
Q

allows two separate blood bag to be connected via their PVC tubing without breaching the integrity of either container

A

Sterile connection device

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7
Q

Uses to freeze plasma, liquid components may be placed in a standard -18 degree C or colder freezer

A

Plasma freezer

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8
Q

storage devices include:

A

refrigerators
freezers
platelet agitators

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9
Q

how many anticoagulant -preservative for every 100 mL of whole blood targeted for collection

A

14mL

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10
Q

whole blood must be stored at what temperature

A

1-6 C

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11
Q

Quality control indicator for this component are NOT routinely measure

A

Whole blood

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12
Q

red blood cells is separated from whole blood by what methods

A

Centrifugation
Apheresis
Sedimentation (less commonly)

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13
Q

AS (additive solution ) must be added to the RBC component within how many days

A

3 days

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14
Q

RBC WITH additive solution, resulting in a finished product with a hematocrit of

A

55% to 65%

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15
Q

RBC WITHOUT additive solution must have a finished hematocrit of

A

65% to 80%

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16
Q

this component must be drawn by a single nontraumatic venipuncture and the concentrate must be prepared within 8 hrs of collection

A

Platelet

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17
Q

Platelets derived from whole blood

A

Random Donor Platelet (RDP)

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18
Q

Platelet product obtain from apheresis donation

A

Single Donor Platelet (SDP)

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19
Q

how to store platelet concentration

A

Room temp
20-24 C with constant agitation

20
Q

RDP should contain how many platelets

A

5.0 x 10^10 platelets

21
Q

SDP should contain at least how many platelets

A

3.0 x 10^11 platelets

22
Q

it is the removal of white blood cell from blood or blood components prior to transfusion

A

Leukocyte reduction or leukoreduction

23
Q

SDP should only contain how many residual white blood cells

A

5.0 x 10^6 residual white blood cells

24
Q

RDP should only contain how many residual white blood cells

A

8.3 x 10^3 residual white blood cells

25
at least how many percent of the original component must be recovered after leukoreduction
85%
26
it protects against transmission of CMV to patients at increased risk of CMV disease
leukoreduction
27
frozen within 8 hours
FFP - fresh frozen plasma
28
frozen within 24 hrs
PF24- plasma frozen within 24 hrs
29
FFP and PF24 can be stored for 1 years at what temp
-18C
30
FFP & PF24 can be stored for 7 yrs at what temp
-65 C
31
thawed temperature
30 - 37 C
32
FFP can be manufactured into
cryoprecipitate and cryo-poor plasma
33
What is the volume of FFP or PF24 from apheresis
as much as 800mL
34
what is the volume of a unit of FFP or PF24 from whole blood
200-375 mL
35
most often used for transfusion or plasma exchange in patients with thrombotic thrombocytopenia purpura
CPP - cryo-poor plasma
36
cryoprecipitate pooled in the transfusion service laboratory using an open system must be transfused with how many hours
4hrs
37
FDA and AABB recommended a minimum dose of gramma irradiation of ____ to the central portion of the blood unit
25Y
38
irradiation may be achieved by using what radioactive sources
cesium-137 cobalt-60 x-ray
39
it is often transfused during the neonatal period or in infants younger than 4 months of age due to their small blood volume
aliquoted blood products
40
it allows multiple blood components to be transfused at a single event
pooled components
41
T/F multiple units of red blood cells are NOT typically pooled together, but ither product types may be pooled
TRUE
42
platelets pooled in an open systems must be transfused within how many hrs
4rhs of pooling
43
it is stored for up to 10 yrs for those patients with rare phenotypes, for autologous use
frozen, deglycerolized RBCs
44
-most widely used -increases the cryoprotective power of the glycerol, thus allowing slow, uncontrolled freezing process -provides storage at -65 C or below
high glycerol (40% weight per volume)
45
Cryoprotection of the glycerol in minimal, and a very rapid, more controlled freezing procedure is require -liquid nitrogen is routinely used for this method
Low glycerol (20% weight per volume)
46
used to treat patients with hemophilia A and have almost completely replaced cryoprecipitate as the product of choice
Factor VIII concentrates