Component 2 Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

Acrosome reaction

A

Acrosome enzymes digest the corona radiata and the zona pellucida

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Allele

A

A version of a gene at a given locus which codes for an altered phenotype

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Allele frequency

A

Proportion of all the genes in the gene pool

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Allopatrick speciation

A

Revolution of a new species from isolated populations by a geographical boundary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Capacitation

A

Removal of glycoproteins and cholesterol coat which increases permeability of the membrane to Ca+ and increases chances of bonding to allow acrosome reaction to occur

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Carrier

A

Heterozygous for one dominant allele and one mutant recessive allele

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Cortical reaction

A

Fusion of cortical membranes with oocyte membrane due to calcium ions being transported into the cytoplasm for SER. This causes zona pellucida to expand and harden

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Dehiscence

A

Opening of the anther releasing pollen grains

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

DNA ligase

A

Enzyme that joins together portions of DNA by catalysing the formation of a phosphodiester bond

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Dormant

A

Active growth of the seed is suspended

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Electrophoresis

A

Separates molecules on the basis of size by rate of migration under an applied voltage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Epigenetics

A

The control of gene expression by modifying DNA or histories which does not effect the nucleotide sequence

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Evolution

A

Change in allele frequency and the average phenotype of the population over time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Founder effect

A

The loss is genetic variation in a new population established by a very small number of individuals from a larger population

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Fruit

A

Structure developing from ovary wall containing one or more seeds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Gene

A

Sequence of dna that codes of a polypeptide and occupies a specific locus on a chromosome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Gene pool

A

All alleles present of all the individuals in a population at a given time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Genetic drift

A

Change in allele frequency due to chance in a small population

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Germination

A

When the seed becomes a photosynthesising plant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Hybrid

A

Off spring is a cross of different species

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Linked

A

Genes are on the same chromosome and therefore do not segregate independently in meiosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Non disjunction

A

Fault cell divisions no in meiosis where one of the daughter cells receives two copies of one chromosome and the other receives none

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Plasmid

A

Small circular loop of DNA bacteria which is double stranded

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Polyploidy

A

Having more than two complete sets of chromosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Primer

A

Single strands of DNA complementary to larger section of DNA that is going to be copied. Signals polymerisation to start

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Recombinant DNA

A

DNA produced by combining DNA from two different species

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Reproductive isolation

A

Prevents reproduction and gene flow between breeding groups in a species in an environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Restriction endonucleases

A

Cuts sugar phosphate backbone at specific restriction sites

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Reverse transcriptase

A

Catalysed the synthesis of DNA from an RNA template

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Seed

A

Contains an embryo and food store within a testa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Sex linkage

A

Gene is located on X chromosome so is more likely in males than females

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Speciation

A

Formation of a new species

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Species

A

Group of organisms that can interbreed to produce fertile offspring

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Stem cell

A

Undifferentiated cell capable of diving to give rise to daughter cells which can develop into any type of cell

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Sticky end

A

Sequence of unpaired bases which are staggered and exposed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Sympatric speciation

A

Evolution of a new species from populations sharing the same environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Test cross

A

Cross with homozygous recessive

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Transgenic

A

Organism genetically modified by the addition of genes from another species

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Trophoblast

A

Cells forming outer layer of blastocyst

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Variation

A

Difference between organisms of the same species

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Mitosis

A

Cell devision forming two genetically identical daughter cells with same number of chromosomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Classification

A

Organisation of organisms into groups according to shared similarities

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

3 domains

A

Eubacteria
Archea
Eukaryotes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Analogous

A

Same function but different structure = not related

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

Homologous structures

A

Same structure different functions = divergent evolution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

Biodiversity

A

Number of species and number of organisms of each species in an environment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

3 types of adaptations

A

Anatomical (body shape = streamlined)
Physiological (leaves fall of with low light intensity and cold)
Behavioural (flowers in spring with pollinating insects)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

Interstitial cells

A

Secrete testosterone for secondary sex characteristics

49
Q

Sertoli cells

A

Nourish cells and protect from immune system

50
Q

Solid ball of cells

A

Morula

51
Q

First hormone secreted

A

GnRH

52
Q

Function of progesterone

A

Produced from corpus luteum

Maintains endometrium and inhibits FSH

53
Q

Function of oestrogen

A
Builds endometrium 
Inhibits FSH 
Stimulates LH
Secondary sex characteristics
Inhibits prolactin and oxytocin
54
Q

Function of FSH

A

Stimulates Graafian follicle
Stimulates oestrogen
I’m

55
Q

2 synergid cells

A

Aid ferlisation

56
Q

3 antipodals

A

Direct nutrients

57
Q

Pollination

A

Transfer of pollen grains from another to nature stigma

58
Q

Self pollination

A

Pollen from anther is transferred to stigma of same flower or plant

59
Q

Cross pollination

A

Pollen transferred from anther to stigma on a flower of a different plant of same species

60
Q

Ensuring cross pollination

A
Dichogamy 
Anther below stigma 
Male and female flowers 
Male and female plants 
Genetic incompatibility
61
Q

Why is maize a fruit

A

Testa fuses with ovary wall

62
Q

What is the testa formed from

A

Integuments and lignin

63
Q

Codominant

A

Both alleles have an affect on phenotype of heterozygous as both are expressed eg. Blood type AB

64
Q

Incomplete dominance

A

Phenotype of the heterozygous is half way between the two alleles

65
Q

Dihybrid cross

A

Cross between two individuals for two genes of different chromosomes
Assumes all allele combinations are equally likely and down to random assortment

66
Q

Recognising linkage

A

Cross over value

Kai squared

67
Q

Critical value

A

Degrees of freedom = number of sums -1

Use 0.05 probability value

68
Q

Mutations

A

Change in amount arrangement structure of DNA

69
Q

When do mutations occur

A

Crossing over in prophase 1

Non disjunction in anaphase 1/2

70
Q

Increased rate in mutations

A

Ionising radiation

Mutagenic agents eg. Agent orange

71
Q

Type of mutations

A

Genepoint
Chromosome
Aneuploidy
Polyploidy

72
Q

Gene point mutation

A

DNA not copied correction

73
Q

Chromosome mutation

A

Damaged or broken chromosome not repaired correctly

74
Q

Aneuploidy mutation

A

Chromosome is lost or added through non disjunction

75
Q

Polyploidy mutation

A

Double number of chromosomes due to

  • endomitosis
  • fusion of two haploid cells
  • defect in spindle fibres
76
Q

Types of gene mutation

A
Substitution 
Addition
Deletion 
Inversion 
Duplication
77
Q

Sickle cell anaemia

A
Substituting of val to glu
Change in tertiary
Insoluble 
Stick together
Sickle shaped 
Reduces oxygen binding
78
Q

Chromosome mutation

A

Change in structure and number of whole chromosomes

Eg. Breaks and doesn’t rejoin or non disjunction

79
Q

Down’s syndrome

A

Down’s syndrome
Extra chromosome 21 from nondisjunction of oocyte

Translocation downs when a bit breaks off and attaches to another chromosome

80
Q

Proteins that’s regulate cell division

A

Protooncogenes

Tumour suppressor genes

81
Q

Malignant cancer

A

Cells break off and travel in blood to form secondary tumour = metastasis

82
Q

2 ways of epigenetixs

A

Histone modification

DNA methylation

83
Q

4 types of variation

A

Heritable
Non inheritable
Continuous
Discontinuous

84
Q

Heritable variation

A

Mixing of parental genotypes
Crossing over
Random assortment
New allele combinations

85
Q

Non inheritable

A

Environmental influences determine phenotype
Eg. Diet exercise
Not passed on

86
Q

Continuous

A

Multiple genes polygenic
Graduation between extremes
Genetic and environmental

87
Q

Discontinuous

A

Single gene mono genic
Discreet variables
Genetic only
Not gradation

88
Q

Causes of variation

A

Mutation
Crossing over
Independent assortment
Random gamete formation
Environmental influence on cytoplasmic level (non inheritable)
Environmental influences on gene expression (epigenetics)

89
Q

4 types of selective agents

A

Environmental factors eg. Fire global warming
Human influence eg. Antibiotics weed killers
Inter specific competition
Intraspecifc competition g

90
Q

3 types of selection

A

Stabilising
Directional
Disruptive

91
Q

Selection pressure

A

Environment factor that can alter the frequency of alleles in a population when it is limiting

92
Q

Natural selection

A

Increased chance of survival and reproduction of organisms with phenotypes suited to their environment enhancing the transfer of favourable alleles between generations

93
Q

Selection

A

Process that better adapted organisms are more likely to survive and breeed and pass on characteristics

94
Q

Bottleneck

A

Disaster killed all by few individuals which changes alleles frequency

95
Q

How many new species arise

A

Polyploidy

Isolation = restriction of gene flow

96
Q

Reproductive isolation

A

Prevent of reproduction and gene flow between breeding groups in a species

97
Q

Prezygotic isolation

A
Geographical 
Behavioural
Morphological
Gamete isolation
Seasonal
98
Q

Postzygotic

A

Hybrid inviability
Hybrid sterility
Hybrid breakdown

99
Q

Harvey Weinberg features

A
Large population
No mutations 
Random mating 
No selective agents 
No immigration or emigration
100
Q

Harvest Weinberg equations

A
P = frequency of dominant allele 
Q = frequency of recessive allele
P2 probability of homozygous dominant 
Q2 probability of homozygous recessive 
2pq probability of heterozygous
101
Q

Sanger sequencing

A
Cut up DNA 
Add dideoxynueotide to present polymerisation 
Mark end nucleotide with marker 
Add stop nucleotides 
Gel electrophoresis
102
Q

Aims of human genome

A

determine order of bases in genome

Identify genes and mapping

103
Q

Chloroquine

A

Delays haemoglobin digestion by the parasite

104
Q

Getting the vector

A

EDTA to destabilise cell wall
Detergent
NaOH
Centrifuge

105
Q

Two gene markers

A

Amphicillin

Tertracycline

106
Q

Where is the gene for insulin

A

In tetracyline gene

107
Q

GM tomatoes

A

Add gene with complementary sequence to the gene that codes for pectin which break down the tomatoes

108
Q

Gene therapy

A

A working copy of the gene in placed into cells that contain a non functioning gene or repair gene by changing expression

109
Q

Somatic cell therapy

A

Replacing fault genes with correct copies in certain body tissues so genes can’t be inherited

110
Q

Germ line

A

Gene is inserted into embryo or gamete or all new cells contain new gene

111
Q

Duchenne muscular dystrophy cause

A

Deletion creates frame shift
Lack of dystrophin so muscles break down and are replaced by fibrous tissue and fatty deposits

Sex linked m

112
Q

Treatment for DMD

A

Drisapersen injections which restore reading frame by being complimentary to the mutated DNA part so section is not translated

113
Q

Autologous cells

A

Cells from same individual

114
Q

Allogenic cells

A

Donor of same species

115
Q

Xenogenic

A

Cells from another species

116
Q

Synergic cells

A

From genetically identical organism

117
Q

Benefits of a scaffold

A

Cells can attack
Delivers and retains cells
Porous for diffusion
Biodegradable

118
Q

Types of stem cells

A

Embryonic
Adult
Genericalll reprogrammed by viruses

119
Q

Uses of stem cells

A

Tissue engineering
Cell based therapies
Screen for new drugs