Complications of pregnancy and labour Flashcards
Risk factors for gestational hypertension
- Primigravida
- First conception with new partner
- PmHx/ Family hx g HTN
- DM, chronic HTN, renal insufficiency
- APLA
- Older age >40
Gestational hypertension vs preexisting hypertension
Pre-existing: HTN prior to 20 weeks
Gestational hypertension: HTN developing after 20 weeks in previously normotensive woman
Pre Eclampsia: HTN with new onset proteinuria or adverse conditions
Eclampsia: one or more GTCs in setting of pre eclampsia
Maternal complicaitons from gestational hypertension
- Liver and renal dysfunction
- Seizures
- Abruption
- LV failure, pulmonary edema
- DIC
- HELLP syndrome
- Hemorrhagic stroke
Side effects of tocolytics
- Indomethacin: closure of ductus arterious early, GI bleed, N/V, worsening asthma, renal issues
- Nifedipine: Hypotension
PPROM less than 34 weeks management
Goal: maintain pregnancy
Manage: expectant- many will deliver in 1 week
Steroids; yes
Abx: yes (ampicillan and erythromycin)
PPROM greater than 34 weeks management
Goal: deliver
Manage: Induce vaginal labour or section
Steroids; No (not past 34 weeks)
Abx: Not unless needed for GBS
Risk factors for preterm labour
- Multiples
- ** history of preterm labour**
- infection
- smoking
- low socioeconomic status
- uterine abnormalities
- bleeding in late pregnancy
Betamethasone
Steroid for lung maturation in preterm babes
Benefits: lungs, decreased intraventricular hemorrhage, decreased necrotizing enterocolitis
Risks: Detrimental in maternal DM
Interventions for short/ partially opened cervix
- Cerclage- sews cervix shut
2. Prostaglandins
Investigations in maternal hypertension
- Urine: protein
- Creatinine, BUN, uric acid (10X less GA)
- INR, platelets, PTT, fibrinogen
- LFTs (ALT, AST, LDH, Bili)
- Fundoscopy
- Reflexes
Treatment of pre-eclampsia
- Deliver baby/placenta
- IV BP meds
- MgSO4 for seizure prophylaxis in mom
- Epidural will help
Rh Disease path
Path: mom becomes sensitized to fetal blood cells after exposure in utero/delivery. Makes ab to fetal RBC
Fx: usually affects second rh incompatible child (need time for ab IgG to be produced)
Causes hemolytic disease of the newborn *
Indications for Rho-Gam
- Rh- bleeding during pregnancy (300ug covers 30cc fetal blood)
- 28 weeks to all Rh-
- Postpartum at delivery/within 72h if baby is Rh+
- Amniocentesis, abortion, chorionic villi sampling
- Ectopic pregnancy
Investigations in Rh disease
Kleihauer-Betke test tells how much fetal blood in maternal circulation (if thought to be greater than 30mL)
Differential diagnosis of small for dates
- Wrong dates
- IUGR
- Fetal demise
- Oligohydramnios