Complications of Pregnancy Flashcards

1
Q

Spontaneous Abortion

A

Intrauterine pregnancy at less than 20 weeks…After 20 weeks considered still birth
Overall, almost 20% of all clinically recognized pregnancies terminate in spontaneous abortion… MCC of early pregnancy

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2
Q

Threatened Abortion

A
Os closed, unpredictable outcome
Slight bleeding
Abdominal cramping
Cervical os is CLOSED
Uterine size compatible with dates
Treat with bed rest
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3
Q

Inevitable Abortion

A
Os open, products of conception have not passed, pregnancy cannot be saved
Moderate bleeding
Moderate to severe uterine cramping
Low back pain
Cervical os is DILATED
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4
Q

Incomplete Abortion

A
Os open, some products of conception have passed
Heavy bleeding
Moderate to severe abdominal cramping
Low back pain
Cervical os is DILATED
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5
Q

Complete Abortion

A

Os may be open or closed, products of conception have passed
Bleeding may be heavy or minimal
Moderate to severe abdominal cramping
Low back pain
Fetus and placenta are completely expelled

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6
Q

Missed Abortion

A

Pregnancy did not develop

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7
Q

Lab Work-up For Recurrent Pregnancy Loss

A

Assessment of uterine structure: HSG, US
Rule out lupus (anticardiolipin antibody, lupus anticoagulant)
TSH

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8
Q

Ectopic Pregnancy Presentation

A
1-2 months of amenorrhea
Morning sickness
Breast tenderness
Diarrhea, urge to defecate
Malaise and syncope
Lower abdominal/pelvic pain: Sudden and severe, Especially adnexal (lateralizing to one side)
Referral of pain to shoulder
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9
Q

Ectopic Pregnancy Diagnosis & Treatment

A

Laparoscopy is definitive

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10
Q

Ectopic Pregnancy Medical Management

A

Methotrexate or Misoprostel given systemically for EARLY ectopic pregnancy who are:
Hemodynamically stable
Are willing and able to comply with post treatment follow-up
Have an hCG ≤ to 5000 mIU/mL
Have no fetal cardiac activity
Size of ectopic is

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11
Q

Hydatidiform mole

A

Most common Gestational Trophoblastic Disease
Benign neoplasm of the chorion in which chorionic villi degenerate
Occurs when a single sperm fertilizes an egg without a nucleus
Partial – a fetus or evidence of an amniotic sac is present
Complete – no fetus or amnion is found
Have a tendency to become choriocarcinoma

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12
Q

Hydatidiform mole Treatment

A

D & C immediately
*Weekly quantitative B-hCG
After two decreasing weekly tests, interval is increased to monthly x 6 months, then every 2 months for a total of one year
No further investigation if hCG levels decrease to normal
No pregnancy until hCG levels remain normal for a minimum of 1 year!

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13
Q

Choriocarcinoma

A

Rare
Highly malignant GTTD
May follow HM, invasion mole, abortion, normal pregnancy, ectopic pregnancy
Causes ulcerating surfaces into the endometrial cavity
Malignant tumor cells enter the circulation and are transported to lungs, brain etc

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14
Q

Presentation of placenta previa

A
Painless bleeding in 3rd trimester
Bright red blood
May have shock symptoms if bleeding severe
VS stable
FHT (fetal heart tones) normal
Fetal activity present
*NO vaginal or speculum exam should be done
Diagnosis best made with ultrasound
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15
Q

Abruptio Placentae (placental abruption) Presentation

A

Vaginal bleeding: Mild to severe (amount does not correlate with degree of separation)
*Abdominal pain or back pain
Uterine contractions
Uterine tenderness
Nonreassuring fetal heart rate pattern
All pregnant women with abdominal pain, uterine contractions and vaginal bleeding need to have this ruled out

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16
Q

Placenta Accretas

A

the placenta attaches too deeply into the wall of the uterus

associated with a history of prior cesarean section, history of uterine instrumentation or surgery, or placenta previa

17
Q

Hyperemesis Gravidarium diagnosis

A

Persistant, severe, intractable vomiting during pregnancy
Wt loss of 5% or more of pre-pregnancy wt
+ Ketonuria not from other causes in the 1st trimester

18
Q

Medical Therapy For Hyperemesis Gravidarium

A

First line: Vitamin B6+ Doxylamine, Unisom (OTC)
Second line: DC Doxylamine and try prochlorperazine (Compazine) or metaclopramide (Reglan)
Third line or if severe requiring hospitalization due to dehydration: Odansetron (Zofran)
May be related to cardiac defects and cleft palate