Complications of L&D Flashcards
leading cause of fetal m&m in US?
preterm delivery
what is considered low birthweight?
< 2500g
prematurity => increased risks of what?
Resp'y distress syndrome hyaline mem dis intraventricular hemorrhage sepsis NEC
RFs for PTL:
PROM chorioamnionitis placental abruption maternal low bw previous PTL low SES multiple gestation uterine anomalies maternal preeclampsia, infection, dis
what is the only FDA-approved tocolytic?
ritodrine
most tocolytics prolong gestation by how much? Why does this help?
48h. Helps allow betamethasone tx for fetal lung maturity.
ritodrine and terbutaline are what kind of drug? How do they work?
beta-agonists (bind to and activate B2 R’s => increased cAMP => sequestration of Ca2+ in SR, inh of MLCK)
SEs of ritodrine & terbutaline?
HA
tachycardia
anxiety
rare pulmonary edema & death
how does magnesium sulfate work?
is a calcium blocker & membrane stabilizer
SEs of magnesium:
flushing
HA
fatigue
diplopia
what is a toxic mag level? Signs of toxicity?
10mg/dL resp'y depression pulm edema hypoxia cardiac arrest loss of DTRs
what’s the best way to r/o mag tox?
serial reflex checks
SE’s of nifedipine:
HA
flushing
dizziness
how should tocolytics be dosed?
Loading dose then maintenance doses.
how does indomethacin work?
blocks COX => decreases PG level
indomethacin is ass’d w/what in fetus?
premature closure of ductus arteriosus
pulm HTN
oligohydramnios 2/2 renal failure
what % of pg’ies end with PTD?
10%
how long will it usually take for labor to start in a pt w/premature ROM?
24-48h without intervention
what is the tampon test?
inject a dye into amniotic sac. Watch for it to come out vagina onto tampon. If it does, ROM has occurred.
when is the risk of prematurity = to the risk of infection in a pt w/PPROM?
b/w 32 and 36 weeks.
what med is indicated in PPROM and why?
ampicillin +/- erythromycin, b/c it prolongs the onset of labor
how long are tocolytics usually admin’d after PPROM?
48h to admin a course of corticosteroids