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Pharmacology Try 2 > Complications > Flashcards

Complications Flashcards

1
Q

ACE Inhibitors

A

persistant nonproductive cough, angioedema, hypertension

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2
Q

ARB Inhibitors

A

angioedema, hypertension

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3
Q

Calcium Channel Blockers

A

Reflex tachycardia, peripheral edema, constipation, toxicity

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4
Q

Alpha Adrenergic Blockers

A

dizziness/fainting

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5
Q

Centrally Acting Alpha 2 Agonists

A

dry mouth, drowsiness/sedation, rebound hypertension, black or sore tongue, leukopenia

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6
Q

Beta Adrenergic Blockers

A

bradycardia, nasal stuffiness, AV block, bronchospasm

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7
Q

Vasodilators

A

dizziness, headache, hypotension, cyanide toxicity

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8
Q

Digoxin

A

toxicity: GI effects (anorexia, nausea, vomiting, abdominal pain), CNS effects (fatigue, weakness, diplopia, blurred vision, yellow-green or white halos around eyes)

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9
Q

Nitrates/Nitroglycerine

A

headache, orthostatic hypotension, reflex tachycardia, tolerance

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10
Q

Adenosine

A

flushing, nausea, bronchospasms, prolonged asystole

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11
Q

Amiodarone

A

bradycardia, cardiogenic shock, pulmonary disorders

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12
Q

Atropine

A

dry mouth, blurred vision, photophobia, urinary retention, constipation

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13
Q

Statins

A

muscle aches, hepatotoxicity, rhabdomyolysis, peripheral neuropathy

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14
Q

Cholesterol Absorption Inhibitor

A

muscle aches, hepatotoxicity, rhabdomyolysis, peripheral neuropathy

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15
Q

Beta 2 Adrenergic Agonists

A

tachycardia, palpitations, tremors

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16
Q

Methylxanthines

A

irritability/restlessness

toxicity: tachycardia, tachypnea, seizures

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17
Q

Inhaled Anticholinergics

A

dry mouth and eyes, urinary retention

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18
Q

Glucocorticoids

A

insomnia, psychotic behavior, hyperglycemia, peptic ulcer, fluid retention, increased appetite

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19
Q

Leukotriene Modifiers

A

elevated liver enzymes,

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20
Q

Antitussives

A

drowsiness, dizziness, constipation

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21
Q

Expectorants

A

drowsiness, dizziness, constipation

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22
Q

Mucolytics

A

drowsiness, dizziness, constipation, aspiration, bronchospasm

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23
Q

Decongestants

A

anticholinergic effects, drowsiness

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24
Q

Antihistamines

A

anticholinergic effects, drowsiness

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25
Q

Glucagon

A

nausea and vomiting, rebound hypoglycemia

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26
Q

Levothyroxine

A

tachycardia, restlessness, diarrhea, weight loss, decreased bone density, heat intolerance, insomnia

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27
Q

Methimaxole

A

skin rash, pruritus, abnormal hair loss, GI upset, paresthesias, periorbital edema, joint and muscle pain, jaudice, agranulocytosis, thrombocytopenia

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28
Q

Somatropin

A

hyperglycemia, hypothyroidism

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29
Q

Desmopressin and Vasopressin

A

hyponatremia, seizure, coma

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30
Q

Epoetin Alpha

A

hypertension

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31
Q

Filgrastim and Pegfilgrastim

A

bone pain, leukocytosis

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32
Q

Oprelvekin

A

fluid retention, blurred vision, cardiac dysrhythmia

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33
Q

Iron Preparations

A

stain teeth, dark/tarry stool

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34
Q

Anticoagulants

A

hemorrhage, heparin induced thrombocytopenia, GI discomfort, bleeding/bruising, toxicity/overdose

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35
Q

Antiplatelets

A

prolonged bleeding, gastric bleeding, thrombocytopenia

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36
Q

Thrombolytics

A

serious bleeding, hypotention, possible anaphylactic reaction

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37
Q

Antacids

A

constipation, hypophosphatemia, diarrhea, renal impairment, hypermagnesemia

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38
Q

Proton Pump Inhibitors

A

osteoporosis, pneumonia, acid rebound

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39
Q

Histamine 2 Receptor Antagonists

A

osteoporosis, pneumonia, decreased libido, lethargy, depression, confusion

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40
Q

Promethazine

A

drowsiness, anticholinergic effects, EPS

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41
Q

Metoclopramide

A

drowsiness, diarrhea, restlessness, EPS, tardive dyskinesia

42
Q

Ondansetron

A

headache, EPS

43
Q

Scopolamine

A

blurred vision, sedation, anticholinergic effects

44
Q

Antidiarrheals

A

constipation, drowsiness, dry mouth, blurred vision

45
Q

Stool Softeners

A

fluid and electrolyte imbalances, GI irritation, hypermagnesemia

46
Q

Loop Diuretics

A

hypovolemia, ototoxicity, hyponatremia, hyperglycemia, digoxin toxicity, lithium toxicity

47
Q

Thiazide Diuretics

A

hypovolemia, hyponatremia, hyperglycemia, digoxin toxicity, lithium toxicity

48
Q

Potassium Sparing Diuretics

A

hyperkalemia, impotence, menstrual irregularities

49
Q

Osmotic Diuretics

A

pulmonary edema, fluid and electrolyte imbalances, thirst, dry mouth

50
Q

Alpha Adrenergic Blockers for Urinary Hesitancy

A

decreased libido, headache, dizziness, excessive salivation, abdominal cramps, diarrhea

51
Q

Anticholinergic Medications for Overactive Bladder

A

anticholindergic effects, drowsiness, dyspepsia

52
Q

Erectile Dysfunction Medication

A

hypotension, priapism (erection lasting longer than 4 hrs), vision impairment, hearing loss, headache, flushing

53
Q

Aminoglycosides

A

ototoxicity, nephrotoxicity

54
Q

Cephalosporins

A

Clostridium difficile, hypersensitivity

55
Q

Fluoroquinolones

A

hepatic toxicity, renal toxicity, tendonitis or tendon rupture

56
Q

Nitrofurantoin

A

brown discoloration to urine, renal toxicity

57
Q

Penicillins

A

hypersensitivity and possible anaphylaxis

58
Q

Tetracyclines

A

tooth discoloration in children under 8

59
Q

Glycopeptide

A

ototoxicity, nephrotoxicity, red man syndrome

60
Q

Antifungal

A

hepatic toxicity, renal toxicity

61
Q

Antimalaria

A

psoriasis, retinopathy

62
Q

Antitubercular

A

neuropathy, hepatotoxicity, rifampin turns tears/saliva/urine/sweat red

63
Q

Bisphosphonates

A

musculoskeletal pain, esophagitis and GI discomfort, jaw pain, atrial fibrillation

64
Q

Disease-Modifying Antirheumatic Drugs

A

increased risk of infection, bone marrow suppression, GI ulceration, retinal damage (hydroxychloroquine)

65
Q

Antigout

A

GI distress, rash and fever

66
Q

Antianxiety

A

CNS depression, paradoxical response, withdrawal symptoms, risk of abuse/overdose

67
Q

Selective Serotonin Reuptake Inhibitors

A

weight gain, sexual dysfunction, fatigue, drowsiness

68
Q

Serotonin and Norepinephrine Reuptake Inhibitors

A

weight gain, sexual dysfunction, fatigue, drowsiness

69
Q

Tricyclic Antidepressants

A

anticholinergic effects, orthostatic hypotension, cardiac dysrhythmias, decreased seizure threshold

70
Q

Mono-Amine Oxidase Inhibitors

A

CNS stimulation, orthostatic hypotension, hypertensive crisis

71
Q

Lithium

A

GI distress, fine hand tremors, polyuria, hypothyroidism, renal toxicity

72
Q

Typical Antipsychotics

A

sedation, extrapyramidal effects, anticholinergic effects, tardive dyskinesia, agranulocytosis, neuroleptic malignant syndrome, seizures

73
Q

Atypical Antipsychotics

A

agranulocytosis, weight gain, diabetes, dyslipidemia, orthostatic hypotension, extrapyramidal effects

74
Q

ADHD Stimulants

A

insomnia, headache, suppressed appetite, abdominal pain

75
Q

ADHD Nonstimulants

A

GI upset, insomnia, mood swings

76
Q

Benzodiazepines

A

amnesia, respiratory depression, drowsiness, dizziness

77
Q

Disulfiram

A

drowsiness, headache, metallic taste, hepatotoxicity

78
Q

Methadone

A

sedation, respiratory depression, paradoxical CNS excitation

79
Q

Cholinesterase Inhibitors

A

bradycardia, chest pain, weak pulse, sweating, dizziness, weak/shallow breathing, increased urination, seizures, trouble swallowing

80
Q

Anti-Parkinson’s Medications

A

muscle twitching, headache, dizziness, dark urine, orthostatic hypotension

81
Q

Anticonvulsants

A

anemia, leukopenia, Steven’s-Johnson syndrome, CNS depression, headache, weight gain, nausea, seizures, drowsiness, hypotension, respiratory depression, gingival hypertrophy, diplopia, hirsutism, hepatotoxicity

82
Q

Antiglaucoma

A

systemic effects of beta blockers: bradycardia, heart failure, bronchospasm
brown discoloration of iris, retinal detachment

83
Q

Nonsteroidal Anti-inflamatory drugs

A

GI discomfort and ulceration, renal impairment, hypersensitivity

84
Q

Acetaminophen

A

nausea and vomiting, hepatotoxicity, long term therapy: hemolytic anemia/leukopenia/neutropenia/thrombocytopenia

85
Q

Opioid Analgesics

A

orthostatic hypotension, constipation, urinary retention, blurred vision, respiratory depression, abstinence synrome

86
Q

Cervical Ripening Drugs

A

nausea, headache, tremor, elevated temperature, tachysystole

87
Q

Oxytocin

A

intense uterine contractions, uterine hyperstimulation, uterine rupture, water intoxication

88
Q

Methylergonovine

A

potent vasoconstriction, hypertension, headache

89
Q

Terbutaline

A

nervousness, headache, nausea/vomiting, hyperglycemia, severe palpitations, chest pain, pulmonary edema

90
Q

Nifedipine

A

hypotension, headache, nausea, flushing

91
Q

Magnesium Sulfate

A

warmth, flushing, respiratory depression, diminished DTRs, decreased urine output, pulmonary edema

92
Q

Betamethasone

A

fluid retention, elevated blood pressure, maternal hyperglycemia and increased WBC

93
Q

Saw Palmetto

A

headache, altered platelet function

94
Q

Valerian Root

A

drowsiness, headache, nervousness

95
Q

St. John’s Wort

A

headache, sleep disturbances, phototoxicity, constipation

96
Q

Echinacea

A

fever and nausea, anaphylaxis

97
Q

Ginkgo

A

dizziness, stomach upset, vertigo

98
Q

Glucosamine

A

nausea, heartburn

99
Q

Omega-3 fatty acids

A

nausea, diarrhea

100
Q

Melatonin

A

morning grogginess, lower body temperature, vivid dreams

Pharmacology Try 2 (6 decks)

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