Complete Blood Count CBC with differentials Flashcards
Hemoglobin Hgb In RBC
Male 13.8 - 16.9 g/dL Female 11.8 - 14.7 g/dL Critical < 6.6, > 17.9 g/dL 1 unit of RBC = +1.0 Hgb
WBC differential “Leukocytes”
Neutrophils, Eosinophils, Basophils, Lymphocytes, Monocytes
RBC
Male 4.1- 5.9 mill/cmm Female 3.8 - 4.9 mill/cmm 1 unit of RBC = +1.0 Hgb
Hematocrit Hct RBC in 100 mL of blood
Male 38.6 - 48.0 % Female 34.5 - 43.9 % Critical < 19.6, > 55.9 % Approx x3 Hgb +/- 3%
WBC
3700 - 10,300 / cmm Critical < 2500, > 30,000
Neutrophil Bands (Immature)
0 - 3 % of total WBC; “Shift to Left”; if high = Bandemia
Platelet (thrombocytes) Count
150,000 - 350,000 /cmm Critical < 30,000, > 1,000,000 /cmm Bleeding tendency < 50,000 /cmm Spontaneous CNS/GI bleed < 5,000 /cmm
Basophils
0 - 2 % of total WBC; if high leukemia; if low corticosteroids, allergic reactions, acute infections
Segmented (Mature) Neutrophils
42 - 75 % of total WBC 1400 - 6500 /cmm 1ST line defenese Life span 10 hrs
CD4
T-lymphocyte; HIV1/AIDS
Absolute Neutrophil Count (ANC) = Total # of neutrophil granulocytes in blood
Normal > 1500 Mild 1000 - 1500 Moderate < 1000 Severe < 500 risk for infection
Eosinophils Antigen/Antibody
0 - 5 % of total WBC if high asthma, hay fever, drug sensitivity, parasitic infection if low, adrenal steroids
Lymphocytes
18 - 48 of WBC T-lymphocytes for immune deficiencies are CD4, CD3, CD34 B-lymphocytes are natural killers
CD3
T-lymphocyte Efficacy of OKT3 (orthoclone immunosuppressive drug to reduce acute rejection of organ transplant)
Monocytes Immature Macrophages
0 - 9 % of total WBC