complement system Flashcards
1
Q
A termed “Complement” was given by
A
Paul Erlich
2
Q
awarded a Noble Prize for
elucidating the nature of complement.
A
Jules Bordet
3
Q
Complement activation Promotes
A
- Activation of immune system
- Opsonization
4
Q
Leads to inflammation and
tissue damage
A
Chronic Activation
5
Q
APR produces by
A
hepatocytes
6
Q
protein inactivated form
A
zymogen
7
Q
protein activated form
A
holoenzyme
8
Q
plasma complement proteins are synthesized in
A
liver
9
Q
main goal of complement system
A
cell lysis
10
Q
two major APR
A
- C-reactive protein
- Serum amyloid A
11
Q
plasma complement proteins synthesized in liver except in
A
C1
12
Q
C1 is produced and composed of what?
A
-produced by epithelial cell and factor B
- composed of adipose tissue
13
Q
Early complement components
A
C1, C2, C3, C4
14
Q
3 complement system or pathway
A
- classical pathway
- alternative pathway
- lectin pathway
15
Q
plays a major role as natural defense system
A
antibody independent pathway
