competitive and non competitive inhibitors Flashcards
inhibitors
limits enzyme activity + reduce ror
competitive inhibitors
complementary to active site of enzymes so they compete with the substrate for the active site
increasing the substrate concentration (for CI)
increase the rate of reaction more substrate molecules mean they are more likely to collide with enzymes and form enzyme-substrate complexes
non competitive inhibitors
attaches to the enzyme at the allosteric site , which alters the shape of the active site and therefore prevents the substrate from binding to it since it’s no longer complementary
increasing the substrate concentration (for NCI)
cannot increase the rate of reaction once more, as the shape of the active site of the enzyme remains changed and enzyme-substrate complexes are still unable to form