Competency 6.1.12 Flashcards

1
Q

Physiological Sites of Vitreous Attachment

A
  • The vitreous is loosely attached to the inner limiting membrane of the retina
  • Stronger sites of vitreo-retinal adhesion are at:
    • Vitreous base (very strong)
    • Optic disc margins (fairly strong)
    • Perifoveal (fairly weak)
    • Peripheral Blood vessels (usually weak)
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2
Q

Pathological Sites of Vitreous Attachment

A
  • Lattice degeneration
  • Vitreomacular traction
  • Retinal neovascular vessels e.g. in DR
  • Snailtrack degeneration
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3
Q

What is Lattice Degeneration?

A
  • is a thinning of the retina that happens over time
  • most with this condition never have any symptoms or a loss in vision
  • prevalent in around 8% of the population however it is found in around 40% of those who have had a retinal detachment
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4
Q

How does Lattice Degeneration Cause Retinal Detachment?

A
  • Lattice degeneration causes a RD by premature PVD and tractional tears.
  • The vitreous overlying an area of lattice degeneration are synchytic however the attachments either side of this area are stronger than usual.
  • Tears may develop after a PVD in the area affected by lattice degeneration
  • Atrophic holes may lead to RD
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5
Q

What is Retinoschisis?

A
  • degeneration of the peripheral retina which causes the retina to split into two different layers
  • split often occurs at the level of the outer plexiform layer
  • results in severing of neurons and therefore a complete loss of visual function in the affected area
  • present in around 5% of the population and is more common in hypermetropic patients
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6
Q

Retinoschisis Symptoms

A

It is often asymptomatic as it lack the vitreo-retinal traction required to cause flashes/floaters, even if the RS is located posterior to the equator the patient seldom notices a field defect.

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7
Q

Retinoschisis Signs

A
  • usually bilateral
  • typically begins by involving the extreme infero-temporal peripheral fundus.
  • appears as a smooth dome-shaped elevation of the retina
    o elevation is smooth and relatively immobile compared to the opaque and corrigated appearance of a rhegmatogenous RD
  • The lesion may progress until it has involved the entire circumference of the peripheral retina
    o The typical form usually stays out here
    o The reticular type is more likely to spread posteriorly
  • The presence of a pigmented demarcating line is likely to indicate RD rather than retinoschisis
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8
Q

What is a Posterior Vitreous Detachment?

A
  • separation of the vitreous body from its sites of attachment posteriot to the vitreous base
  • This occurs due to synchysis of the vitreous humour which forms small fluid filled cavities.
  • PVD is a normal age related event and PVD prevalence increases with age.
  • usually be a spontaneous event, it can be induced by the likes of surgery, trauma or uveitis
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9
Q

Posterior Vitreous Detachment Prevalence

A

Only around 10% of those inder 50 years of age have had a PVD however this is around 66% of those over 70 years.

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10
Q

How Often Does Posterior Vitreous Detachment lead to Retinal Detachment

A

Normally 10% of those with a symptomatic PVD will have suffered a retinal tear, however if there is a haemorrhage this rises to 60%.

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11
Q

The Usual Sequence of Events of a PVD

A
  • Perifoveal detachment
  • Foveal separation
  • Detachment from posterior retina as far as equator
  • Initially disc attachment may remain
  • Peripheral detachment as far as vitreous base (only attachment to remain)
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12
Q

Posterior Vitreous Detachment Symptoms

A
  • Flashes
    o Described as lightning arc-esq
    o Can be induced by eye or head movement
    o Mostly seen in temporal periphery
    o More noticeable in dim illumination
  • Floaters
    o Mobile vitreous opacities
    o Most evident against a bright pale background
    o Can be Weiss ring/vitreous blood
  • Blurred vision
    o Can be due to dispersed haemorrhage
    o Can be due to floaters on visual axis
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13
Q

Posterior Vitreous Detachment Signs

A
  • Posterior hyaloid membrane can sometimes be seen on posterior examination
  • Haemorrhage may be indicated by small red cells in the vitreous cavity
  • Weiss ring
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14
Q

What is a Retinal Break?

A
  • often occurs due to vitro-retinal traction at sites of adhesion, whether than be physiological or pathological
  • When there is a retinal break the vitreous fluid has access to the area behind the retina.
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15
Q

Retinal Break Prevalence

A

Retinal breaks occur in around 20% of eyes with a symptomatic PVD and belived to be around 8% of eyes in the general population

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16
Q

Retinal Break Timing

A
  • Usually present sooner after symptoms of a PVD
  • Tear formation can be delayed in rare cases
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17
Q

Retinal Break Location

A
  • Tears aossciated with a PVD usually located in upper retina
  • More often temporal than nasal
  • Macular breaks related to PVD are rare
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18
Q

Retinal Break Morphology

A
  • Retinal breaks may be flat or may have aossicated area of sub-retinal fluid
  • If there is more than 1 disc diameter of fluid form the edge of the break then this is defined as a retinal detachment
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19
Q

Types of Retinal Tears

A
  • Horseshoe Tears
  • Operculated Tears
  • Retinal Holes
  • Dialysis
  • Giant Retinal Tear
20
Q

Features of Horseshoe Tears

A

o Consists of a flap
o Its apex is pulled anteriorly by the vitreous
o Base remains attached to retina

21
Q

Features of Retinal Holes

A

o Round/oval
o Usually smaller than tears
o Lower risk of RD
- If RD occurs then is usally:
 slowly progressing
 in a young female myope
o PVD not necessarily present

21
Q

Features of Operculated Tears

A

o The flap is completely torn away by the vitreous leaving a round/oval break
o The patch of torn away retina can be seen in the vitrous cavity

22
Q

Features of Dialysis Retinal Detachment

A

o Circumferencial tear along ora-serrata
o Usually due to trauma
o Vitreous remains attached at posterior part of break
o Appears as large RD
o Slowly progressive in absence of PVD

23
Q

Features of Giant Retinal Tear

A

o Involving 90 degrees or more of retinal circumference
o Vitreous remains attached to anterior part of break (unlike dialysis)
o Most often located at immediately posterior to ora-serrata but can be at equator

24
What is a Rhegmatogenous Retinal Detachment?
- often characterised by a retinal break often due to vitreo-retinal traction - allows for liquified vitreous to travel under the retina which separates it from the RPE - A RD will almost never occur in this manner if the vitreous is not liquified and there is no traction.
25
Rhegmatogenous Retinal Detachment Risk Factors
- Myopic eyes - Vitreous degeneration - PVD - Lattice degeneration - Snailtrack degeneration - Vitreous loss during cataract surgery
26
Distribution of Breaks in Rhegmatogenous Retinal Detachment
- Where are Breaks located? o 60% superotemporal o 15% superonasal o 15% inferotemporal o 10% inferonasal - Multiple Breaks? o Half of eyes with retinal detachment have two holes - Often within the same quadrant
27
Rhegmatogenous Retinal Detachment Symptoms
- Flashes and floaters (due to PVD) o Location of photopsia is of no use in locating the primary break - Curtain-esq peripheral VF defect appears o Sometimes can resolve and not be present upon waking in the morning due to spontaneous absorption of SRF o The quadrant of VF affected will often be the oppose quadrant of the primary break o A lower VF defect if more often appreciated earlier by patient than a superior defect - Loss of central vision o Could indicate macular involvement o Or obstruction of visual axis of large detachment
28
Rhegmatogenous Retinal Detachment Signs
- RAPD o Present in eyes with extensive RD - IOP o Normally around 5mmHg lower than normal eye o If extremely low then a choroidal detachment could be present o Can be increased if there is Uveitis associated with trauma - Iritis o Usually mild - Tobacco Dust o Highly suggestive of retinal break o Pigment cells located in anterior vitreous - Blood cells or inflammatory cells are also highly specific - Retinal Breaks - Visible retinal detachment
29
Appearance of a Fresh Rhegmatogenous Retinal Detachment
- RD has a convex shape - Slightly opaque - corrugated appearance (due to retinal oedema) - Loss of underlying choroidal pattern - BVs appear darker than in flat retina - SRF extends up until ora-serrata (unless caused by macular hole) - Macular pseudohole - Will be quite mobile
30
Appearance of a Longstanding Rhegmatogenous Retinal Detachment
- Retinal thinning o Due to atrophy - Intraretinal Cysts o May develop if detachment has been present for about 1 year - Subretinal Demarcation Lines o Caused by proliferation of RPE cells at junction of flat and detached retina o Takes around 3 months to develop o Does not limit spread of SRF
31
What is a Tractional Retinal Detachment?
- Tractional RD is caused by contraction of fibrovascular membranes in areas of vitreo-retinal traction - PVD in eyes with DR is often incomplete and more gradual which is thought to be due to leakage of plasma into vitreous gel - If a break occurs in a tractional RD then it assumes the characteristics of a rhegmatogenous RD and progresses rapidly.
32
Tractional Retinal Detachment Causes
- Proliferative DR - Retinopathy of prematurity - Penetrating posterior segment trauma
33
Tractional Retinal Detachment Symptoms
- Flashes and floaters usually absent as not associated with an acute PVD - VF defect o Slowly developing over months of years
34
Tractional Retinal Detachment Signs
- RD has concave form - Breaks usually absent - Retinal mobility is severely reduced with no shifting fluid - Less expansion of SRF - Highest elevation occurs at site of traction
35
What is an Exudative Retinal Detachment?
- characterised by the accumulation of SRF in the absence of a retinal break or traction - often due to fluid leaking out of vessels out of vessels and accumulating under the retina. - If the RPE is able to cope and pump out the fluid into choroidal circulation then there is no RD
36
Exudative Retinal Detachment Causes
- Choroidal tumours o Intraocular tumour should be considered the cause of exudative RD until proven otherwise. - Inflammation (incl posterior scleritis) - Bullous central serous chorioretinopathy - Iatrogenic - Choroidal Neovacularisation
37
Exudative Retinal Detachment Symptoms
- no flashes as no vitreoretinal detachment - Floaters may be present only if there is associated vitritis - VF defect may develop suddenly and progress rapidly
38
Exudative Retinal Detachment Symptoms
- Convex profile - Surface is smooth and not corrugated - Very mobile - Shifting fluid detaches the area of retina where it is located
39
What is Pneumatic Retinopexy?
- Outpatient procedure - a bubble of gas alongside laser/cryotherapy is used to seal a rhegmatogenous RD - This procedure is usually reserved for the treatment of uncomplicated RD with a small retinal break in the peripheral retina.
40
Advantages and Disadvantages of Pneumatic Retinopexy
Advantages: - Quick - Minimally invasive Disadvantages: - Success rated lower than conventional scleral buckling
41
What is Scleral Buckling?
Is a surgical procedure where material sutured onto the sclera creates a buckle which aims to close retinal breaks by: - placing the RPE next to the sensory retina - Reduce dynamic vitreoretinal traction
42
Complications of Scleral Buckling
- Diplopia o Due to mechanical effect of buckle o Early spontaneous resolution is typical - CMO o Occurs in 25% but usually responds to treatment o Can also be epiretinal membrane - Anterior Segment Ischaemia o Due to vascular compromise - Infection - Elevated IOP
43
Indications for a Vitrectomy
- When retinal breaks cannot be visualised due to e.g haemorrhage or debris etc o Scleral buckling prognosis is poor if any breaks are missed - When retinal breaks are unlikely to be closed by scleral buckle alone o Giant tears - Tractional RD - Prevention of tractional retinal detachment
44
Goals of a Vitrectomy
- Separate the posterior hyaloid from retinal surface - To remove the epiretinal tissue to release retinal traction - Close retinal breaks if present
45
Vitrectomy Complications
- Intraoperatively o retinal breaks o choroidal haemorrhage - Postoperatively o Retinal breaks and rhegmatogenous RD o Retinal fold o Inflammation o Raised IOP o Cataract