Community paediatrics and psychiatry ||| Flashcards
What are the 4 fields of developmental skills?
- Gross motor
- Vision and fine motor
- Hearing, speech and language
- Social, emotional and behavioural
When considering developmental milestones, what is the definition of median age?
The age when half of a standard population of children achieve that level
When considering developmental milestones, what is the definition of limit ages?
The age by which the developmental milestones should have been achieved
How do you assess developmental age of a preterm baby?
When do you stop correcting for age?
Calculate it from the expected date of delivery
At 2 years of age
Define normal development
Steady progress in all 4 developmental fields with acquisition of skills occurring before limit ages are reached
What should be considered when evaluating a child’s development (5)?
- Each skill field separately
- The sequence of developmental progress
- The stage the child has reached for each skill field
- If progress is similar in each skill field
- Only at the end, the child’s overall developmental profile and how that relates to the child’s age
At what age does each developmental progress accelerate the fastest (4)?
- Motor: 1st year of life
- Vision and fine motor development: from 1 year onwards
- Hearing, speech and language: from 18 months
- Social, emotional and behavioural: from 2.5 years of age
What are the milestones of gross motor function (5)?
Newborn - Flexed posture 7 months - sits without support 1 year - Stands independently 15-18 months - walks independently and steadily 2.5 years - runs and jumps
What are the milestones of vision and fine motor (5)?
newborn - Follows face or light by 2 weeks
7 months - transfers objects from hand to hand
1 year - pincer grip (10 months), points
15-18 months - immature grip of pencil, random scribble
2.5 years - draws
Define global developmental delay, what age does it become apparent at?
Delay in acquisition of all skill fields, apparent around first 2 years of life.
What investigations would you do for someone with possible global developmental delay (7)?
Do investigations for possible cause
- Cytogenic testing
- Metabolic e.g. thyroid tests, LFTs, bone chemistry, U+Es, etc
- Infection e.g. congenital infection screen for cytomegalovirus
- Imaging e.g. CT/MRI brain scans, skeletal survey
- Neurophysiology e.g. EEG for seizures
- Histopathology i..e. nerve, skin and muscle biopsy
- Other e.g. hearing, vision, psychiatry etc
What are the possible causes of abnormal development and learning difficulty?
- Prenatal (5)
- Perinatal (3)
- Postnatal (6)
- Other (3)
Prenatal
- Genetic i.e. Down syndrome
- Cerebrovascular i.e. stroke
- Metabolic i.e. hypothyroidism, phenylketonuria
- Teratogenic i.e. alcohol/drug abuse
- Congenital infection i.e. rubella, cytomegalovirus, toxoplasmosis, HIV
Perinatal
- extreme prematurity i.e. intraventricular haemorrhage/periventricular leucomalacia
- birth asphyxia i.e. hypoxic-ischaemia encephalopathy
- metabolic i.e. symptomtaic hypoglycaemia, hyperbilirubinemia
Postnatal
- infection i.e. meningitis/encehalitis
- anoxia i.e. suffocation, near drowning seizures
- trauma i.e. head injury
- metabolic i.e. hypoglycaemia, inborn errors of metabolism
- cerebrovascular i.e. stroke
- nutritional deficiency i.e. food intolerance, maternal deficiency (breast fed)
Other
- chronic illness
- physical abuse
- emotional neglect
Define cerebral palsy
An umbrella term for a permanent disorder of movement and/or posture and of motor function due to a non-progressive abnormality in the developing brain
What are the 3 types of cerebral palsy?
- Spastic cerebral palsy
- Dyskinetic cerebral palsy
- Ataxic (hypotonic) cerebral palsy
What is the pathophysiology of spastic cerebral palsy and the key signs on a neurological examination (3)?
- Damage to the upper motor neurone pathway
- Limb tone is persistently increased (spasticity) with associated brisk deep tendon reflexes and extensor plantor responses
- Sometimes there is initial hypotonia particularly of the head and trunk
What are the 3 types of spastic CP and how do they often present?
- Unilateral (hemiplegia)
- unilateral involvement of the arm and leg.
- At 4-12 months, they present with fisting of affected hand, a flexed arm, a pronated forearm, asymmetric reaching, hand function or toe pointing when lifting the child. - Bilateral (quadriplegia)
- all 4 limbs affected often severely.
- The trunk is involved with a tendency to opisthotonus, poor head control and low central tone - Bilateral (diplegia)
- all 4 limbs but the legs are affected to a much greater degree than the arms.
- Motor difficulties are apparent with functional use of the hands, walking is abnormal.
What is the pathophysiology of dyskinetic cerebral palsy and the key signs on a neurological examination (6)?
Damage to basal ganglia and extra-pyramidal pathways.
Presents with:
- Floppiness
- Poor trunk control
- Delayed motor development in infancy.
- Abnormal movements towards the end of the first year of life.
- Muscle tone is variable
- Primitive reflex patterns predominate
What is the pathophysiology of ataxic (hypotonic) cerebral palsy and the key signs on a neurological examination (6)?
Usually genetically determined
- Early trunk and limb hypotonia
- poor balance
- delayed motor development.
- incoordinate movements
- intention tremor
- Ataxic gait may be evident later
What are the early features of CP (4)?
- Abnormal limb and/or trunk posture and tone in infancy with delayed motor milestones
- Feeding difficulties, with oromotor incoordination, slow feeding, gagging and vomiting
- Abnormal gait once walking is achieved
- Asymmetric hand function before 12 months of age
What are the ddx of abnormal motor development (4)?
- Central motor deficit e.g. CP
- Congenital myopathy/primary muscle disease
- Spinal cord lesions e.g. spina bifida
- Global developmental delay as in many syndromes or of unidentified cause
What can you look for in a neurological exam in the developmental screening (7)?
- Abnormal posture/symmetry
- wasting
- tone and power
- deep tendon reflexes
- clonus
- plantar responses
- cranial nerves
Key delays when performing a developmental assessment according to age: 1. Prenatal (2) 2. Infancy (3) 3. Preschool (5) 4. school age (6) 5 any age (1)
Prenatal
- Dysmorphic features
- Abnormal neurological behaviour i.e. tone, feeding, movement, seizures, visual inattention
Infancy
- Global developmental delay
- delayed or asymmetric motor development
- vision or hearing concerns
Preschool
- speech and language delay
- abnormal gait
- Clumsy motor skills
- poor social communication skills
- behaviour - stereotypical, overactivity, inattention
School age
- problems with balance and coordination
- learning difficulties
- attention control
- hyperactivity
- specific learning difficulties
- social communication difficulties
Any age
1. loss of skills
What are possible reasons for speech and language delay (5)?
- Hearing loss
- Global developmental delay
- Difficulty in speech production from an anatomical deficit e.g. cleft palate
- Environmental deprivation/lack of opportunity for social interaction
- Normal variant/familial pattern
What are the different types of speech and language disorders (5)?
- Language comprehension
- language expression - inability or difficulty in producing speech whilst knowing what is needing to be said
- intelligibility and speech production such as stammering (dysfluency), dysarthria or verbal dyspraxia
- Pragmatics (difference between sentence meaning and speakers meaning), construction of sentences, semantics and grammar
- social/communication skills (ASD)
How do you define Asperger syndrome?
Asperger syndrome refers to a child with the social impairments of an ASD but at the milder end, and near-normal speech development
How is ASD diagnosed?
Observation of behaviour and use of formal standardized tests (Autism diagnostic interview, Autism Diagnostic observation schedule and diagnostic interview for social and communication disorders)
How is ASD managed (2)?
- Applied behaviour analysis - behaviour modification approach that helps to reduce ritualistic behaviour, develop language, social skills and play, and to generalize use of all these skills.
- Being in an appropropriate educational placement