Communication and Signalling (b) Hydrophobic Signals and Control of Transcription Flashcards
Hydrophobic signalling molecules can diffuse directly through…
The phospholipid bilayers of membranes, and so bind to intracellular receptors.
The receptors for hydrophobic signalling molecules are…
Transcription factors
Transcription factors are…
Proteins that when bound to DNA can either stimulate or inhibit initiation of trascription
The steroid hormones oestrogen and testostrone are examples of…
Hydrophobic signalling molecules
- Steroid hormones bind to…
Specific receptors in the cytosol or the nucleus.
- The hormone-receptor complex moves to the…
Nucleus where it binds to specific sites on DNA and affects gene expression.
- The hormone-receptor complex binds to…
Specific DNA sequences called Hormone Response Elelments (HREs). Binding at these sites influences the rate of transcription, with each steroid hormone affecting the gene expression of many different genes.
