communication and homeostasis Flashcards
features of a good communication system
cover the whole body so the action of all cells and tissues can be co-ordinated
enable localised communication between cells
enable long distance communication between cells (widespread)
enable specific communication (targets specific cells to respond only)
be rapid (allowing fast response to rapid changes)
enable long term responses (more hormonal)
enable short term responses (more neuronal)
how do cells communicate with each other
cell signalling
2 communication systems: neuronal and hormonal
communicate to create a co-ordinated response
identify/recognise each other via cell signalling
cell signalling neuronal vs hormonal
both involve cell signalling molecules which are complementary to the shape of their receptor molecules on the cell surface membrane
neuronal often short term
hormonal long term
what may a cell signalling molecule be
protein
amino acid
lipid
glycoprotein
another organic chemical
examples of cell signalling molecules
hormones
antibodies
histamines
cytokines like interleukins
example of cell signalling from communicable diseases
in immune response, T helper cells bind to specific APCs (clonal selection) before clonal expansion is triggered by cytokine interleukin 1
T helper cells then bind to specific B lymphocytes stimulating plasma cell production by cytokine interleukin 2
what is the nervous system
interconnected network of neurones that signal to each other across synapses via neurotransmitters
what are neurones
specialised cells which can conduct electrical impulses very quickly to enable rapid responses e.g. reflexes
what do cells within endocrine glands release
hormones directly into the blood
what is a hormone
a chemical messenger which has a specific shape that is recognised by specific target cells
hormonal system: long or short term responses?
both
example of LT hormone response
LT stress response e.g. illness or injury. body cannot sustain bursts of energy mediated by adrenaline and noradrenaline so other hormones e.g. cortisol are important.
cortisol affects cellular metabolism leading to stimulation of glucose synthesis
nervous control vs hormonal control:
transmission
N: elec and chem transmission (nerve impulses and chemicals across synapses)
H: chem transmission (hormones) through blood system
nervous control vs hormonal control:
speed
N: rapid transmission and response
H: slower transmission and relatively slow-acting (adrenaline is an exception)
nervous control vs hormonal control:
ST/LT
N: often short term changes
H: often long term changes
nervous control vs hormonal control:
pathway
N: pathway is specific (through nerve cells)
H: pathway not specific (blood around whole body) but is target specific
nervous control vs hormonal control:
size of response
N: responses often v localised e.g. one muscle
H: response may be very widespread e.g. growth
nervous control vs hormonal control:
cell signalling molecules
both involve cell signalling molecules which are complementary to the shape of the receptor they interact w
both work together for the co-ordinated responses in the body e.g. in fight/flight response, sympathetic nervous system stimulates adrenal gland to release adrenaline
cell signalling definition
the process bay which cells communicate with each other for co-ordination of bodily functions
cell recognition
cells work together
trigger reaction inside of target cell
e.g. hormone
explain how a glycoprotein can act as a receptor
cell signalling molecule binds to a complementary receptor (complementary to shape of ligand) e.g. hormones/ neurotransmitters to trigger a response
may be involved in endocytosis
has a specific shape
outline 3 roles of glycoproteins in membranes
allow for recognition of ‘self’ by the immune system
act as antigens
stabilises membrane forming H bonds w/ H2O molecules
act as receptors for cell-signalling molecules
binding sites for hormones
examples of changes to the internal environment
blood glucose concentration
water potential of blood
internal temperature
pH of blood
blood pressure
examples of changes to the external environment
humidity
light intensity
external temperature
new/sudden sound
pressure on skin
what’s another word for an environmental change
stimulus
what’s another word for a change in behaviour
response
examples of responses to external stimuli
seasonal change in temperature causes thick fur development of rabbits (white and brown)
appearance of predator/prey causes fight/flight and hormone release
give 2 reasons why both plants and animals need to be able to respond to changes in their environment
to avoid being eaten and to obtain access to resources
state an organ that is associated with maintaining the internal environment of a mammal and state the role it plays
pancreas releases insulin to regulate and maintain blood glucose levels
definition of homeostasis
maintenance of a stable internal environment around a set point despite internal/ external environmental changes
what does homeostasis include
thermoregulation
blood glucose concentration
blood salt concentration
water potential of blood
blood pressure
blood pH (conc of CO2)
what is the thermoregulation important for
enzyme activity
why is controlling blood glucose level necessary
needed for respiration
affects water potential
why is controlling blood salt concentration necessary
affects the water potential
affects blood pressure
why is controlling water potential of the blood necessary
it affects blood pressure
why is controlling blood pressure necessary
ensures blood delivered efficiently and without damage to walls of blood vessels/ heart
why is controlling blood pH necessary
decreases pH which affects enzymes
what is feedback
when effectors bring about a response they change the condition in the body and this new condition will be detected by receptors (i.e. the input has changed) which in turn will affect the response
what is negative feedback
a change initiates a series of events and negative feedback is a mechanism that reverse the change bringing the system back to optimum
what is overshoot in a homeostatic mechanism
it takes time to respond to a stimulus and the response may cause an overshoot and so homeostasis involves fluctuations around the optimum
what does negative feedback ensure
conditions inside a living organism remain within a relatively narrow range
what is overshoot minimised by
gradually cutting off corrective mechanisms
quick response
antagonistic control
positive feedback details
the mechanism that increases a change, taking the system further away from the optimum
tends to be harmful, but not always
not involved in homeostasis
examples of positive feedback
opening of channels in neurones
blood clotting
during hypothermia
during birth
examples of positive feedback: opening of channels in neurones
Na+ enters the axon due to stimulus
potential difference becomes less negative
voltage gated Na+ channels open
more Na+ enters
action potential fired
examples of positive feedback: blood clotting
platelets attract more platelets which accelerates clotting