Communicating Trial Results

Question 1

6 examples of who to communicate CT results to:

Answer 1

General public
Participants
Policy Makers
Med Schools
Ethical board
community
Health workers

Question 2

Why do we need to communicate CT results? 5

Answer 2

Ethical responsibility
Maintain good relationships
increase speed of the impact
May be really good messenger to get results out
Demonstrate importance of trials and research

Question 3

What about using peer review journals to communicate results?

Answer 3

Necessary but not always best way to communicate

Question 4

Who is peer review journals good for?

Answer 4

Researchers
not public
policy makers want a policy orientated summary

Question 5

What should we also consider when communicating results?

Answer 5

What we want them to know, what they want to know, language, education, time, messenger

Question 6

What do different groups want to know? 4

Answer 6

Patients: Personal implications
Policy makers: Cost and feasibility
Scientists: Robust methodology
Clinicians: technical details

Question 7

What does the declaration of Helsinki say about clinical trial result communication?

Answer 7

All studies including human subjects must be registered in a public database before subject recruitment and all results must become publicly available

Question 8

So what is the new law regarding clinical trial registration?

Answer 8

From July 1st, international committee of medical journal editors decides only trials included in CT registry will be considered for publication

Question 9

Where to register clinical trials? 3

Answer 9

WHO has a data set, ISRCTN- numerical, clinicaltrials.gov

Question 10

Why register? 4

Answer 10

Prevents selective publication and reporting
Prevents duplication of methods
Helps patients and public know what trials are planned
Helps ethics boards

Question 11

So what do CT do when publishing?

Answer 11

Also print reg number

and make results free and publicly available