Communicable diseases, disease prevention and the immune system Flashcards
Define communicable disease
Can be passed from one organism to another between individuals of the same of different species
Define pathogen
Disease-causing microbes/microorganisms
Define disease vector
Any agent that carries and transmits an infectious pathogen into another organism
What can be a vector?
- Organisms
- Inanimate medium
Give two examples of an inanimate medium that can be a vector
- Water
- Dust particles
List the types of pathogen
- Bacteria
- Viruses
- Bacteriophages
- Protoctista (Protists)
- Fungi
How many bacteria are pathogenic?
A small number of thousands of bacterial species are pathogenic
Are bacteria eukaryotes?
No, their prokaryotes
How can you classify bacteria?
By shapes
What are the main types of bacteria?
- Spheres (cocci)
- Rods (bacilli)
- Spirals
Give three examples of sphere/cocci bacteria
- Diplococci
- Streptococci
- Tetrad
- Staphylococci
- Sarcina
Give three examples of rods/bacilli bacteria
- Chain of bacilli
- Flagellate rods
- Spore-former
Give three examples of spiral bacteria
- Vibrios
- Spirilla
- Spirochaetes
What is the cell wall structure of bacteria?
Two main types of cell wall that react differently to Gram staining
What are viruses?
Non-living infectious agents
How much smaller are viruses compared to bacteria?
50x
How many viruses are pathogenic?
All of them
What is the structure of a virus?
Basic structure of some genetic material (DNA or RNA) that is surrounded by protein
What are bacteriophages?
Viruses that attack bacteria
How do bacteriophages attack bacteria?
They take over the cell and use them to replicate, killing the bacteria in process
Are protoctista (protista) eukaryotic organisms?
Yes
How many protoctista (protista) are pathogenic?
A small percentage
What do protoctista (protista) cause?
Communicable disease in plants and animals
Protists that cause disease are…
Parasitic
What may protists need to transfer to their hosts?
Vectors
Give an example of diseases that are caused by protists
- Malaria
- Sleeping sickness
Which protist causes sleeping sickness?
Trypanosoma
What is the vector for trypanosoma?
Tsetse flies
Fungi are not usually problematic in animals but the can be … in plants
Devasting
Are fungi prokaryotes?
No, they are eykaryotes
Are fungi multicellular or unicellular?
Frequently multicellular, but occasionally unicellular
Give an example of a unicellular fungi?
Yeast
As fungi cannot photosynthesise, how do they get what nutrients they need?
They absorb nutrients from their environment after releasing digestive enzymes
What are most fungi (other than multicellular)?
Saprophytes
What are saprophytes?
They feed on dead and decaying matter
Some fungi are this (not unicellular)
Parasitic
What do parasitic fungi feed on?
Plants and animals
The fungi that are parasitic are?
Pathogenic and can cause communicable diseases
What do fungi often attack?
The leaves of plants, stopping them photosynthesising
What do fungi produce?
Spores
How do fungi infect? What is their mode of infection?
Spores that can spread huge distances and through crop plants rapidly
What are the two modes of action?
- Damaging the host tissues directly
- Producing toxins which damage host tissue
What causes symptoms?
The damage and the way in which the body of the host responds to the damage
How do viruses cause symptoms, using the mode of action: damaging the host tissues directly?
- Take over the cell metabolism
- The viral genetic material gets into the host cell and is inserted into the hosts’ DNA
- The virus then uses the host cell to make new viruses which then burst out of the cell, destroying it
- Then it spreads to infect other cells
How do some protoctista (protists) cause symptoms, using the mode of action: damaging the host tissues directly?
- Take over cells and break them open as the new generation emerges
- BUT they do not take over the genetic material of the cell
- They simply digest and use the cell contents as they reproduce
- Protists that cause malaria are an example of this
How do fungi cause symptoms, using the mode of action: damaging the host tissues directly?
- Digest living cells and destroy them
How do bacteria cause symptoms, using the mode of action: producing toxins which damage host tissue?
- Most bacteria produce toxins that poison or damage the host cells in some way, causing disease
- Some bacterial toxins damage the host cells by breaking down the cell membranes
- Some bacterial toxins damage or inactivate enzymes
- Some bacterial toxins interfere with the host cell’s genetic material so the cell cannot divide
- These toxins are a by-product of the normal
functioning of the bacteria
Do fungi use the mode of action: producing toxins which damage host tissue?
Yes, some fungi produce toxins which affect the hosts cells and cause disease
What are some abiotic environmental factors?
- Wind
- Water
- Inhalation of spores
- Entry into skin
What are some animal vectors?
- Mosquitoes (malaria, dengue)
- Fleas (bubonic plague)
With human-to-human transmission, why does direct contact mode of transmission work?
Pathogen survives best inside the body
Give examples of diseases caused by the mode of transmission: direct contact in human-to-human transmission
- HIV
- Herpes-viruses
- Ebola
With human-to-human transmission, why does indirect contact mode of transmission work
Pathogen survives in harsh environments
Can pick up the pathogen from surface or air
Give examples of diseases caused by the mode of transmission: indirect contact in human-to-human transmission
- Influenza
- Norovirus
With human-to-human transmission, why does the mode of transmission: droplets work (but not very well)?
Pathogens are in droplets but do not survive long this way
Give examples of diseases caused by the mode of transmission: droplets in human-to-human transmission
- Ebola
- Bordetella pertussis
With human-to-human transmission, why does airborne mode of transmission work?
Pathogens are aerosolised and stay infectious
Give examples of diseases caused by airborne in human-to-human transmission
- Influenza
- Tuberculosis
With human-to-human transmission, how does fecal-oral mode of transmission work?
Through contaminated food or water
Give examples of diseases caused by the mode of transmission: fecal-oral
- Cholera
- Norovirus
- Shigella
What are examples of direct contact in direct transmission in animals?
- Kissing and body fluids
- Direct skin-to-skin contact
- Microorganisms from faeces transmitted on hands
Give examples of diseases caused by the direct transmission in animals: direct contact (kissing and body fluids)
- Bacterial meningitis
- STDs, i.e. HPV (14 million cases annually
Give examples of diseases caused by the direct transmission in animals: direct contact (direct skin-to-skin contact)
- Ringworm
- Athletes foot
Give examples of diseases caused by the direct transmission in animals: direct contact (Microorganisms from faeces transmitted on hands)
- Diarrhoeal disease
What are examples of inoculation in direct transmission in animals?
- Break in the skin
- Animal bites
- Puncture would or shared needles
Give examples of diseases caused by the direct transmission in animals: inoculation (break in the skin)
- HIV/AIDs