Common Receptors Flashcards
Drugs that act as agonists on alpha receptors
Alpha-1: Decongestants (e.g. phenylephrine/oxymetazoline)
Alpha-2: Glaucoma (e.g. topical brimonidine)
Drugs that act as antagonists on alpha receptors
Benign prostatic hyperplasia (e.g. tamsulosin)
Hypertension (e.g. doxazosin)
Drugs that act as agonists on beta receptors
Beta 1: Inotropes (e.g. dobutamine)
Beta 2: Bronchodilators (e.g. salbutamol)
Drugs that act as antagonists on beta receptors
Non-selective beta-blockers (e.g. propranolol, labetalol)
agonists on dopamine receptors
Parkinson’s disease (e.g. ropinirole)
Prolactinoma
antagonists on dopamine receptors
Schizophrenia (antipsychotics e.g. haloperidol)
Anti-emetics (e.g. metoclopramide/domperidone)
Drugs that act as agonists on GABA receptors
Benzodiazepines
Baclofen
Drugs that act as antagonists on GABA receptors
Flumazenil - acts as both an antagonist and antidote to benzodiazepines (particularly in cases of overdose), through competitive inhibition.
Drugs that act as antagonists on Histamine receptors
H1: Antihistamines (e.g. loratadine)
H2: Antacids (e.g. ranitidine)
Drugs that act as agonists on muscarinic receptors
Glaucoma (e.g. pilocarpine)
Drugs that act as antagonists on muscarinic receptors
Atropine (e.g. for bradycardia)
Bronchodilator (e.g. ipratropium bromide, tiotropium)
Urge incontinence (e.g. oxybutynin)
Drugs that act as agonists on nicotinic receptors
Nicotine
Varenicline (used for smoking cessation)
Depolarising muscle relaxant (e.g. suxamethonium)
Drugs that act as antagonists on nicotinic receptors
Non-depolarising muscle relaxants (e.g. atracurium)
Drugs that act as agonists on oxytocin receptors
Inducing labour (e.g. Syntocinon)
Drugs that act as agonists vs antagonists on serotonin receptors
Agonist: Triptans (for acute migraine, e.g. zolmitriptan)
Antagonists: Anti-emetics (e.g. ondansetron)
