Common GI Presentations Flashcards

1
Q

What are the causes of normal vomit?

A
  • Caused by gastroenteritis or being generally unwell.
  • Also caused by upper GI obstruction:
    • Pyloric stenosis
    • Peptic ulcer disease
    • Intussusception
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2
Q

What are the causes of coffee-ground vomit?

A
  • Non-specific gastritis most commonly the cause.
  • Very infrequently a sign of a significant bleed.
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3
Q

What are the common causes of haematemesis?

A
  • Oesophageal or gastric varices.
  • Duodenal ulcer or gastric ulcer.
  • Significant Mallory Weiss tear.
  • The patients are significantly unwell and they often have molena as well.
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4
Q

What is the cause of bilious vomiting?

A

Post-pyloric obstruction

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5
Q

What questions would you ask someone in the hx if they present with vomiting?

A
  • Recent holidays?
  • Strange foods?
    • Dodgy takeaway
  • Anyone else unwell?
  • Change in medications?
    • Worth checking the BNF to make sure they have not been started on anything that is making them vomit.
    • What are their regular medications?
  • Symptoms to suggest infection?
  • PMHx?
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6
Q

Describe how you would assess a patient who is vomiting.

A
  • Full ABCDE assessment
    • Are they actively vomiting?
    • Are they haemodynamically stable?
  • Examination
    • Look at dentition
    • Look at hands
    • Abdominal examination
      • Any abdo pai?
      • Bowel sounds present?
      • NEVER forget to PR.
  • Bloods
    • U&E, CRP, Mg, Bone, Glucose
    • FBC, clotting, XM
    • Venous gas
  • Pregnancy test!
  • Urinalysis
  • CXR/AXR
  • CT Abdo
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7
Q

Describe the management of a patient who is vomiting.

A
  • Treatment of underlying cause
    • MOST IMPORTANT
  • Ensure well-hydrated and electrolytes are corrected.
  • If UGIB
    • Fluid resuscitation
    • Blood products
    • Discussion with GI / surgeons
  • Antiemetics
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8
Q

What are the anti-emetics which can be used in a patient who is vomiting?

How do they work?

What are their side-effects?

A
  • Prochlorperazine
    • Can be sedating
  • Metoclopromide
    • Aids gastric motility
    • Extra-pyramidal side-effects
    • Oculogyric crisis in young women
  • Ondansetron
    • Acts centrally
    • Delays gastric emptying
    • Good in chemotherapy
  • Cyclizine
    • Can give a ‘high’
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9
Q

What is dyspepsia?

A
  • A collection of symptoms:
    • Retrosternal discomfort
    • Bloating / borborygmi (highly active bowel sounds)
    • Heaviness
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10
Q

What are the types of dyspepsia?

A
  • Organic dyspepsia
    • Duodenal ulcer / gastric ulcer
    • Oesophagitis / duodenitis
    • Gastric cancer
    • H. pylori
  • Functional dyspepsia
    • Ulcer type e.g. Epigastric pain
    • Dysmotility type e.g. Early satiety, distension, nausea
    • Reflux type e.g. Retrosternal discomfort
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11
Q

What are the red flag symptoms associated with dyspepsia?

A
  • Weight loss
  • Dysphagia
  • Iron deficiency anaemia
  • Recurrent vomiting
  • Worrying medications
    • Steroids
    • NSAIDs
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12
Q

Describe the treatment of dyspepsia.

A
  • Organic dyspepsia
    • Treatment of underlying cause
    • High dose PPI
  • Functional dyspepsia
    • Lifestyle modification (symptoms can disappear after weight loss)
      • Weight
      • Alcohol
      • Smoking
    • Consider acid suppression
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13
Q

What are the symptoms of GORD?

A
  • Heartburn
    • Retrosternal pain related to eating, lying down.
  • Regurgitation of acid / bile
  • Waterbrash
    • Excess salivation, often acidic
  • Nocturnal cough / wheeze
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14
Q

Describe the treatment of GORD.

A
  • Trial of acid suppression
  • Endoscopy
    • Assess for oesopagitis / hiatus hernia.
    • Assess for Barretts (causes patient to have a higher risk of developing oesophageal cancer).
  • Consider oesophageal manometry and pH impedance
    • May prompt anti-reflux surgery.
  • Important points:
    • GORD may mimic an MI and vice-versa.
    • Oesophageal spasm is a very rare condition
      • Consider an alternatie diagnosis.
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15
Q

What are the 4 key questions to ask a patient who presents with dysphagia?

A
  • Interval
    • Difficulty in initiating swallowing
    • Repeated attempt to ‘get food over’
    • Dysphagia immediately after swallowing
  • Type of food
    • Liquids - suggests possible pharyngeal cause.
    • Solids - mechanical obstruction.
    • Both - likely oesophageal dysmotility.
  • Pattern
    • Intermittent
      • Oesophageal dysmotility
      • Atypical causes
    • Progressive
      • E.g. solids → liquids
      • Organic oesophageal cause
  • Associated features
    • Weight loss
    • Heartburn
    • Cough
    • Odynophagia
    • ?Systemic disease
      • Asthma
      • Scleroderma
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16
Q

Which diseases are likely to represent oropharyngeal dysphagia?

A
  • Previous stroke
  • MND
  • Pharyngeal pouch
  • Parkinson’s disease
17
Q

Describe the assessment of a patient who presents with dysphagia.

A
  • CXR
    • ?Hilar / bronchial mass
    • ?Right-sided consolidation
      • Suggests aspiration
    • Oesophageal fluid level
  • Endoscopy
    • Dysphagia to solids!
    • Weight loss
    • Progressive symptoms
  • Barium swallow
    • Unable to navigate with edoscopy
    • Normal endoscopy
18
Q

What are the differentials for dysphagia?

A
  • Oesophageal stricture
    • Peptic - longstanding reflux oesophagitis
    • Anastomotic
    • Radiotherapy - particularly breast / lung
    • Corrosives - bleach
  • Oesophageal carcinoma
    • Progressive
    • Weight loss
  • Achalasia
    • Absent peristalsis
    • Increased LOS pressure
    • Regurgitation of solid foodstuffs
  • Eosinophilic oesophagitis
    • Intermittent food bolus obstruction
    • Hx of asthma / eczema / atopy
  • Candidiasis
    • Steroid use
    • Immunosuppressed
    • Odynophagia
19
Q

A patient presents systemically unwell, complaining of weight loss and they have iron deficiency anaemia.

This is their endoscopy.

What is the diagnosis?

A

Oesophageal carcinoma

20
Q

What does this CXR show?

A
  • Classical achalasia.
  • Tightening of the LOS towards the end not allowing any food through. Food builds up and eventually stimulates the gag reflex and they vomit it back up.
21
Q

What disease classically gives this appearance on endoscopy?

A
  • Eosinophilic oesophagitis.
  • Concentric rings are classical of this.
22
Q

What are the 6 Fs of abdominal distension?

A
  • Foetus
  • Flatus
  • Faeces
  • Fluid
  • Fat
  • Fatal tumour
23
Q

Describe the assessment of abdominal distension.

A
  • Concise hx
  • Thorough clinical examination
    • Shifting dullness
    • Organomegaly
    • PR
    • Bowel sounds
24
Q

What is the definition of chronic diarrhoea?

A
  • 3 or more loose / liquid stools per day for >4 weeks
  • Stool volume >200mL/day
25
Q

What is osmotic diarrhoea?

A
  • Malabsorbed osmotically active substances e.g. carbohydrates / peptides.
  • Typically resolves with fasting.
  • Often related to laxative abuse.
26
Q

What causes secretory diarrhoea?

A
  • Often stimulated by a toxin e.g. bacteria, or a peptide e.g. VIPoma (vasointestinal peptide).
27
Q

What questions would you ask in the hx of a patient presenting with diarrhoea?

A
  • Duration
    • >4/52 requires further investigation
  • Family Hx
    • GI cancer
    • IBD
    • Coeliac
  • Previous surgery / pancreatic disease
    • Do they have diarrhoea because they have no large intestine or a short bowel?
  • Drugs
    • ABx / PPI / NSAIDs / Alcohol
  • Travel
  • Systemic disease
    • Thyroid / diabetes / connecive tissue disorders
28
Q

What are the features of diarrhoea which point to a specific cause?

A
  • Blood in the stools
    • Often signifies a colonic cause
  • Steattorhoea
    • Failing to flush
    • Pale
    • Fat globules
  • Organic pathology
    • <3 months and continuous
    • Weight loss
    • Nocturnal
29
Q

How would you investigate a patient presenting with bowel symptoms?

A
  • STOOL
    • Culture
    • Faecal elastase
    • Faecal calprotectin (with caution)
  • NEVER FORGET PR
    • Constipated
    • Rectal mass
  • Bloods
    • FBC
    • U&E, CRP
    • TFTs
    • Anti-tTG and immunoglobulins
    • 7-alpha-cholestanone (patients often get diarrhoea after cholecystectomy because cannot absorb bile acid so they need to be given bile acid.)
30
Q

When is a colonoscopy indicated?

A
  • All change in bowel habut > 50
  • Rectal bleeding
  • Weight loss
  • Strong FHx
  • Picture - malignant polyp in the sigmoid colon (can cause diarrhoea with a little PR bleeding).
31
Q

What are the key features of IBD?

A
  • Weight loss
  • Iron deficiency anaemia with thrombocythaemia
  • Slowly progressive
  • Nocturnal symptoms (IBS will NOT have nocturnal diarrhoea; IBD may well have)
  • Extra-intestinal manifestations (shown in the picture)
32
Q

What are the key features of IBS?

A
  • Abdominal pain
  • No bleeding
  • Investigations normal
  • Dietary
    • Gluten hypersensitivity
    • Lactose intolerance
33
Q

What are the components of constipation?

A
  • Passage of hard, infrequent stools <3 / week
  • Straining
  • Incomplete evacuation
34
Q

What is the commonest cause of constipation?

And the other common causes?

A
  • DRUGS
    • Opiates
    • Anticholinergics
    • Iron
  • Diet
    • Poor fibre intake
  • IBS
  • Anorectal disease
    • Strictures
    • Fissures
35
Q

Describe the management of constipation.

A
  • Correct the correctable
    • Change analgesia
    • Rehydrate
    • Treat their infection
    • Manage their diet better
  • Laxatives
    • Osmotic laxatives
      • Lactulose / laxido
      • Don’t lose lon term effect
    • Stimulant laxatives
      • Senna / Bisacodyl
      • Lose long term effect - ‘cathartic colon’
    • Faecal softeners
      • Glycerin suppositories
      • Docusate sodium
      • Phosphate enema