Common Aneuploidies & X-Chromosomal Inactivation

Question 1

True or False?

The X chromosome is known to carry the genes for red-green color blindness, ornithine transcarbamylase, glucose-6-phosphate dehydrogenase, and Factor VIII

Answer 1

True

Question 2

Which of the following chromosomal abnormalities results in the smallest decrease in reproductive fitness?
A. Triploidy
B. Trisomy 13
C. Klinefelter syndrome
D. Turner syndrome
E. Pericentric inversion

Answer 2

E. Pericentric inversion

Question 3

What is the Lyon Hypothesis?

Answer 3

The Lyon Hypothesis states that in any given cell, there is only one active X chromosome