Coma, PVS, Brain death Flashcards
What is a coma?
- unrousable
- psychological unresponsiveness
- eyes closed
- Does not respond to external/internal stimuli
What are the 2 factors which consciousness depends on?
- Cortex for awareness of environment/ content
- Reticular ascending pathway for the awakening system
Causes for decreased consciousness
- Metabolic/toxic
- Seizures
- Damage to reticular activating system
- Causes for raised ICP
What are examples of metabolic/toxic causes for decreased consciousness ?
- Hypoxia
- Hypercapnia
- Drug intoxication
- Hypoglycemia
What happens during persistent vegetative state
Brainstem recovers but cortex does not
There is arousal and wakefulness
There is no awareness or purposeful behaviour
What happens during locked in syndrome?
- Total paralysis below the third cranial nerve nuclei
- Can elevate and depress eyes
- Cannot move eyes horizontally
Stages of Resuscitation
- Airway
- Breathing:
- Hyperventilation : hypoxia, hypercapnia
- Hypoventilation : drug overdose
- Fluctuating: brainstem lesion
-Circulation :
Take blood samples
Establish Pulse, temperature, IV access and stabilise the neck
Examine for presence of meningitis
- History : predictable/ unpredictable incident
- Examination and monitoring
What need to be monitored in resus
- Temperature
- Heart rate
- Blood pressure
- Respiration
- Abdomen
- Meningism
- Fundal examination
Stages of a neuroexamination in a coma patient
- GCS
- brainstem function
- motor function
GCS in a coma patient.
Less than 8
Will not open eyes in response to pain
Grunting or absent vocal response
Weak flexion in response to pain
Brainstem function testing
- Pupillary response
- Corneal response
- Spontaneous eye movements
- Oculo-cephalic movements
- Oculo-vestibular responses
- Respiratory pattern
Testing motor function
- Motor response
- Motor tone
- Tendon reflex
- Seizures
3 Different types of coma
- No focal laterising signs, no meningism
- Menigism, no focal lateral signs
- Focal laterising signs
Causes of coma with meningism
SAH
Meningitis
Encephalitis
Investigation of coma with meningism
CT scan Lumbar puncture: -Apperance -Cell count -Glucose level -Capsular antigen tests