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TERAPEUTICA > COLCHICINA > Flashcards

COLCHICINA Flashcards

GOTA

1
Q

MECANISMO DE ACCION

A

Inhibe la polimerizacion de microtubulos al unirse a la tubulina eevita la migracion de leucocitos, inhibe la produccion de citoquinas

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2
Q

cinetica

A

v/o
met cyp450
vida media 9hs
eliminacion x heces

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3
Q

EFECTOS ADVERSOS

A

tgi
lesion renal
miopatia
neuropatia periferica

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4
Q

indicacion

A

GOTA AGUDA
psoriasis

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5
Q

CONTRAINDICACION

A

insuficinecia renal
insificiencia hepatica
embarazo

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TERAPEUTICA (13 decks)

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