Cofactors Flashcards
0
Q
TPP Vitamin precursor
A
Thiamin
1
Q
TPP Reaction Class
A
Decarboxylation
2
Q
Beriberi Disease
A
Cause: TPP deficiency
Pathology: Headache, malaise, neuropathy
3
Q
Wernicke Encephelopathy
A
Vitamin deficiency: TPP
Pathology: Confusion, abnormal eye movement, ataxia
4
Q
Karsokoff psychosis
A
Vitamin deficiency: TPP
Pathology: Amnesia and confabulation
5
Q
Lipoate vitamin precursor
A
Lipoate
6
Q
Lipoate Reaction class
A
Acyl transfer
7
Q
Lipoate deficiency
A
Nothing observed
8
Q
PLP reaction type
A
Transamination
9
Q
PLP Vitamin precursor
A
Vitamin B6
10
Q
PLP deficiency
A
Seizure, diarrhea, anemia, EEG complication, cant convert tryptophan to niacin
11
Q
Biotin reaction type
A
Carboxylation (adds CO2)
12
Q
Biotin vitamin precursor
A
None
13
Q
Biotin deficiency
A
Scaly dermatitis, thinning of hair, alopecia
14
Q
Cobalamin reaction type
A
methyl transfer
