Coeliac disease Flashcards
1
Q
How common is coeliac disease?
A
-1 in 100-300
-Can occur at any age but peaks in childhood and 50-60s
-Increased risk if present in first degree relatives
2
Q
What causes coeliac disease?
A
-T-cell responds to gluten in the small bowel
-Causes villous atrophy and malabsorption
3
Q
How does coeliac disease present?
A
-Diarrhoea
-Steatorrhoea
-Abdo pain
-Bloating
-N+V
-Aphthous ulcers / angular stomatitis
-Weight loss
-Fatigue (anaemia)
4
Q
How would you investigate a patient with coeliac disease?
A
-FBC / haematinics
-Serology for anti-transglutaminase
-Duodenal biopsy (whilst on gluten diet)
5
Q
What treatment would you consider for someone with coeliac disease?
A
-Lifelong gluten-free diet (ie no wheat, barley, oats)
-Low volume of oats may be tolerable
