Coagulation Modifier Drugs

Question 1

Anticoigulat drugs

Answer 1

1) Heparin
2) Warfarin

Question 2

Antidote for Low-Molecular-Weight Heparin (LMWH)

Answer 2

Protamine Sulphate

Question 3

Strength Differentiation of Warfarin

Answer 3

• 2 mg: Pink
• 3 mg: Brown
• 6 mg: Teal or light blue

Question 4

Warfarin (Coumadin) action

Answer 4

Inhibit vitamin K dependent
(Does not remove vitamin K)

Less Vitamin K - Fever clotting factor - slower blood clot formation

Question 5

Warfarin: Monitor

Answer 5

• Prothrombin Time
• International Normalized Ratio

Question 6

Warfarin: Treatment for toxic effect

Answer 6

• Discontinue the warfarin
• Vitamin K will reverse the anticoagulation within 6 hrs.
• When vitamin K is given, warfarin resistance will occur for up to 7 days.

Question 7

Antidote for Warfarin

Answer 7

Vitamin K

Question 8

Anticoagulants: MOA

Answer 8

Do not break down existing clots

Question 9

Anticoagulants: Contraindications

Answer 9

Warfarin is strongly contraindicated in pregnancy.

Question 10

Patient Education

Answer 10

• Wear medical alert bracelet
• Avoid foods that are high in Vitamin K
  Ex:
• Tomatoes
• Dark leafy green vegetables