coagulation

Question 1

What happens if sterile water is used to dilute PRBC’s?

Answer 1

hemolysis

Question 2

What is a reasonable lower threshold for platelet infusion?
40000
70000
100000
130000
150000

Answer 2

70000

not usually required until platelet count >50000

Question 3

A pool of platelets raises platelet count by how much?

Answer 3

300-50000

Question 4

If a trauma pt is undergoing emergent laparotamy and receives and recieves 10 cell saver units plus 12 prbcs and no clots are in surgical field and venipuncture sites have begun to bleed, what’s the problem?

Answer 4

dilutional thrombocytopenia

Question 5

What is the earliest coagulation disturbance seen in massively transfused patients?

Answer 5

hypofibrinigemia

Question 6

What fibrinogen level is associated with coagulopathies?

Answer 6

<100 mg/dl

normal 200-400

Question 7

What product can be used to treat Hemophilia A?

Answer 7

cryo

or recombinant factor VIII–preferred

Question 8

Which factor is hemophilia a and b

Answer 8

a is a chortage of VII

b is IX

Question 9

conditions producing decreased response to heparin

Answer 9

heparin bids and upregulates ATIII. ATIII then inhibits IX,X,XI, and XII
hepatic insufficiency-ATIII deficiency, ateriosclerotic disease, septicemia, pregnancy, HIT,
drugs-heparin, NTG interaction
neonates/elderly