Coag Test and Fibrinolysis - Lect Flashcards
tilt tube method is the principle behind?
APTT and PT
this method requires gentle tilting of the tube back and forth at the rate of about once per second until a fibrin web is formed.
tilt tube method
wire loop technique is the principle behind?
clot retraction method
wire loop technique uses __ materia
nichrome
wire loop technique employs the use of a wire loop that is passed through the mixture at the ___ until a formed clot adheres to the loop.
rate of two sweeps per second
enumerate the manual techniques
tilt tube method and wire loop technique
enumerate the automated techniques
moving probe and optical density
this technique is immersed in the mixture that is triggered by clot formation
moving probe
this technique detects clot when it is formed in the mixture.
optical density
most common technique in automated devices and the one being measured in a turbid mixture to detect the rate of the formed clot.
optical density
enumerate the tests under secondary hemostasis
lee and white clotting time and slide method
lee and white clotting time screen secondary hemostasis, the ___ pathway
extrinsic and intrinsic pathway
principle of lee and white method
Expose blood to a negatively charged surface (glass)
normal value of lee and white
5-15 mins
normal value of slide method
4-10 mins
sensitivity of slide method clotting time
intrinsic pathway factors
this method is the surface of the glass tube initiates the clotting process. Fibrin string presence indicates clot formation.
clotting time - slide method
PT measures the __
extrinsic and common pathway
APTT measures the __ and common pathway except ___ and __
intrinsic and common pathway except factor XIII and platelets
PT monitors?
coumadin therapy
sample used for PT
citrated plasma - platelet poor plasma
sample used for APTT
citrated plasma - platelet poor plasma
nv of PT
10-15 secs
reagent used in PT
Tissue Thromboplastin, 0.025 M CaCl Solution
APTT monitors the?
heparin therapy
reagent used in APTT
Partial Thromboplastin (substitute for platelet),
CaCl, Activators
activators used in APTTT
Kaolin, Ellagic acid, Celite, Silica