CNS Tissue Ch. 12 Flashcards
What are the two divisions of the nervous system?
- CNS (Central Nervous System) which contains A. The Spinal Cord, and B. The Brain
- PNS (Peripheral Nervous System) which includes A. The nerves, and B. Their ganglia
What and where is the CNS?
Central Nervous System consists of the brain and spinal cord, and they occupy the cranium and vertebral canal. (Dorsal Body Cavity)
What and where is the PNS?
Peripheral Nervous System is outside of the CNS, and includes both spinal nerves and cranial nerves.
Peripheral nerves link all regions of the body to the CNS.
CRANIAL NERVES EXTEND FROM THE BRAIN and carry signals to and from the brain.
SPINAL NERVES EXTEND FROM SPINAL CORD and carry signals to and from spinal cord.
GANGLIA are clusters of neuronal cell bodies located outside of CNS.
What and where is the CNS?
Central Nervous System consists of the brain and spinal cord, and they occupy the cranium and vertebral canal. (Dorsal Body Cavity)
What is Motor Output?
Motor (efferent) signals are carried away from the CNS by nerve fibers of the PNS to innervate muscles to contract and/or glands to secrete
What is Sensory Input?
Sensory (afferent) signals picked up by sensory receptors throughout the body and are carried by nerve fibers of PNS to the CNS.
What exactly does the Nervous System do then? (Big picture)
Processes and interpret SENSORY INPUT and makes decisions on what should be done- a process called INTEGRATION
Dictates a response by activating effector organs (muscles or glands, for example) to produce a MOTOR OUTPUT RESPONSE
What are the regions that Sensory Input and Motor Output serve?
SOMATIC BODY REGION: structures external to the ventral body cavity, i.e. outer tube (skin, skeletal musculature, axial bones) and appendicular bones and muscles.
VISCERAL BODY REGION: contains viscera within the ventral body cavity, i.e. inner tube (digestive tube, lungs, heart, spleen, bladder, etc.) as well as smooth muscle and glands throughout the body.
Tell me about the neuron.
The human body contains billions of neurons.
They are the basic structural unit of the nervous system, they are large, complex cells.
They contain a cell body, and arm-like neuron processes (dendrites and axons) extend from cell bodies.
Conduct electrical impulses from one part of the body to another
Signals travel very rapidly and are transmitted along the plasma membrane in the form of nerve impulses (action potentials)
What are the types of nervous tissue cells?
- NEURONS - excitatory cells
2. NEUROGLIAL CELLS- non-conducting cells that wrap around, nourish, insulate, and protect the delicate neurons.
Describe the cell body of a neuron.
Size varies from 5-140 micrometers.
In most neurons, the plasma membrane of the cell body acts as a receptive surface that receives signals from other neurons!
Has a single nucleus surrounded by cytoplasm.
Cytoplasm contains all the usual organelles as well as CHROMATOPHILIC BODIES (NISSI BODIES) which are free clusters of rough ER and free ribosmes.
NEUROFIBRILS - bundles of intermediate filaments which form a network between chromatophilic bodies and prevent the cell from being pulled apart when subjected to tensile forces.
Where are these neuron cell bodies located?
Most neuron cell bodies are located in the CNS, however, there are clusters of cell bodies in ganglia in the PNS (peripheral nervous system).
Describe the cell body of a neuron.
Size varies from 5-140 micrometers.
In most neurons, the plasma membrane of the cell body acts as a receptive surface that receives signals from other neurons!
Has a single nucleus surrounded by cytoplasm.
Cytoplasm contains all the usual organelles as well as CHROMATOPHILIC BODIES (NISSI BODIES) which are free clusters of rough ER and free ribosmes.
NEUROFIBRILS - bundles of intermediate filaments which form a network between chromatophilic bodies and prevent the cell from being pulled apart when subjected to tensile forces.
Where are these cell bodies located?
Most neuron cell bodies are located in the CNS, however, there are clusters of cell bodies in ganglia in the PNS (peripheral nervous system).
What are axons? (neuron process)
AXONS - The neuron only has one axon which originates from a cone-shaped region of the cell-body called the AXON HILOCK.
Axons have a uniform diameter throughout the length.
Axons are impulse generators and conductors.
They transmit impulses away from the cell body.
What are dendrites? (neuron process)
DENDRITES - Processes that extensively branch from the cell body.
They function as receptive sites for receiving signals from other neurons.
They transmit electrical signals toward the cell body.
What is the length of an axon?
Neurons may be long or short. Axons of motor nerves innervating foot extend from lumbar spine and a single axon can be 3-4 feet long!
How is an axon structure supported?
Neurofilaments, actin microfilaments, and microtubules provide structural strength along length of axon.
This structural support aids in AXONAL TRANSPORT of substances to and from the cell body
Do axons branch?
Axons branch far less frequently than dendrites.
Axon branches develop at more or less 90 degree angles to develop axon collaterals.
Branches usually occur at the terminus of the axon and referred to as TERMINAL BRANCHES
The end in knobs called AXON TERMINALS, also called end bulbs or boutons.
What is the difference between a neuron, nerve fiber, and nerve?
NEURON - Nerve cell
NERVE FIBER - long axon of neuron
NERVE - Collection of parallel running nerve fibers in the PNS
What is a nerve impulse?
Nerve impulses are generated where the axon extends from the axon hillock.
Nerve impulses are conducted along the axon to axon terminals.
Nerve impulses release neurotransmitters from axon terminals into extracellular space (synaptic cleft) where they excite or inhibit neurons or target organs.
So how do neurons interact with each other?
Two neurons are connected by a synapse.
Axon terminal of pre-synaptic neuron and the pre-synaptic membrane in the first neuron.
Neurotransmitters are spewed out from the first neuron through the SYNAPTIC CLEFT.
The 2nd neuron has a postsynaptic membrane (I think) and have a post-synaptic dendrite of post-synaptic neuron.
What is a synapse?
The synapse is the site at which neurons communicate.
Most synapses in the nervous system transmit information through chemical messengers. Signals pass across synapse in one direction.
PRESYNAPTIC NEURON - conducts signal toward a synapse.
POSTSYNAPTIC NEURON - transmits electrical signal away from a synapse.
Most synapses in the CNS function w/ both presynaptic (info-sending) and postsynaptic (info-receiving) neurons; synapses get info from certain neurons and pass the info on to other neurons.
Give me some more detail on a synapse.
Synapses are elaborate cell junction.
SYNAPTIC VESICLES - on presynaptic side.
Synaptic vesicles are membrane bound sacs containing neurotransmitter chemicals that transmit messages across the synapse.
Mitochondria is abundant in axon terminals to provide energy for the secretion of neurotransmitters.
SYNAPTIC CLEFT - Separates the plasma membrane of two neurons.
What is a synapse?
The synapse is the site at which neurons communicate.
Give me some more detail on a synapse.
Synapses are elaborate cell junction.
SYNAPTIC VESICLES - on presynaptic side.
Synaptic vesicles are membrane bound sacs containing neurotransmitter chemicals that transmit messages across the synapse.
Mitochondria is abundant in axon terminals to provide energy for the secretion of neurotransmitters.
SYNAPTIC CLEFT - Separates the plasma membrane of two neurons.
What are the 3 structural classifications of neurons?
- Multipolar neurons: >2 processes; interneurons and motor neurons; 99% of neurons in body
- Bipolar neurons: 2 Processes; special sensory function
- Unipolar (pseudounipolar): 1 process; sensory function
What is a multipolar neuron?
Multipolar neurons possess >2 processes.
Typically have many processes extending from the cell body with multiple dendrites and one axon.
Multipolar neurons make up >99% of neurons in the body
Some examples are interneurons and motor neurons!
Most are interneurons (association neurons) that conduct impulses within the CNS.
What is a bipolar neuron?
Possess two processes that extend from opposite sides of the cell body; one is a fused dendrite and other is an axon.
- Rare
- It is found in some special sensory organs (like the inner ear, olfactory epithelium of the nose, retina of the eye).
What is a unipolar neuron?
- Possess one short, single process near the neuron cell body
- This single process divides into two longer branches: one branch (axon) extends to the CNS (CENTRAL PROCESS) and one branch (“dendritic axon”) extends peripherally to the receptors (PERIPHERAL PROCESS)
- Most start as bipolar neurons during development and are hence called pseudounipolar
- Found in sensory ganglia of the PNS, where they function as sensory neurons
- Common in dorsal root ganglia along spinal cord and the sensory ganglia of cranial nerves