CNS - neurones, NTs and synapses Flashcards

1
Q

what are ions

A

electrically charged chemicals

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2
Q

example of positive ion

A

sodium (Na+)

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3
Q

example of negative ion

A

chloride (Cl-)

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4
Q

what are the charges inside and out of a neurone at rest

A

negative on inside
positive on outside

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5
Q

resting potential of a neurone

A

-70mV

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6
Q

what is an action potential

A

a spike in electric charge in an axon caused by sodium ions crossing the cell membrane - created by depolarising current

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7
Q

how does a stimulus cause an action potential

A
  • causes resting potential to move towards being more positive
  • reaches threshold of -55mV so ion channels open
  • positive ions diffuse in down electrochemical gradient
  • neurone grows more positive and depolarised
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8
Q

what is the result of depolarisation and action potential

A

electrical impulse fires across neurone away from cell body and towards to axon terminal then returns to resting

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9
Q

how does synaptic transmission work

A
  • presynaptic neurone excited by action potential
  • vesicles containing NT fuse with presynaptic membrane
  • NTs enter synaptic cleft
  • they bind to receptors on postsynaptic neurone, this activates the next neurone
  • some NTs then leave the cleft by diffusion, reuptake back into presynaptic neurone or are broken down by enymes
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10
Q

examples of NTs

A

dopamine
glutamate
serotonin

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11
Q

dopamine

A

pleasure and addiction
influences motivation and reward pathway

high/low levels can cause SZ

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12
Q

glutamate

A

cognitive function
memory and learning

excess can cause cell death, then alzheimers/strokes/seizures

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13
Q

serotonin

A

happiness and mood
more serotonin, less depressed

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14
Q

what makes up the CNS

A

brain + spinal cord

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15
Q

frontal lobe

A

at the front
thinking/problem solving

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16
Q

parietal lobe

A

at the top
perception

17
Q

temporal lobe

A

at the bottom
memory/language

18
Q

occipital lobe

A

at the back
visual processing

19
Q

cerebellum

A

coordination

20
Q

brain stem

A

regulates heart rate and body temperature

21
Q

limbic system

A

hypothalamus
hippocampus
amygdala

22
Q

hypothalamus

A

homeostasis
regulates hormones and emotions

23
Q

hippocampus

A

converts STM to LTM

24
Q

left amygdala

A

motivation and reward

25
Q

right amygdala

A

fear conditioning