CNS infection

Question 1

infection of brain substance

Answer 1

Encephalitis

Question 2

Infection of meninges

Answer 2

meningitis

Question 3

Infection of spinal cord

Answer 3

Myelitis

Question 4

Classical triad of meningitis symptoms

Answer 4

Fever

Stiff neck

Altered mental state

Question 5

Symptom of encephalitis

Answer 5

Flu like symptoms before hand

Progressive altered mental state

seizures

Question 6

Symptoms of Anti-VGKC autoimmune encephalitis

Answer 6

Frequent seizures
amnesia
Altered mental state

Question 7

Symptoms of Anti-NMDA autoimmune encephalitis

Answer 7

Flue like prodrome
Prominent psychiatric features
Altered mental state and seizures
Progressing to a movement disorder and coma

Question 8

Meningitis investigations

Answer 8

Blood cultures

Lumbar puncture

Question 9

Encephalitis investigations

Answer 9

Blood cultures
Imaging (CT scan +/- MRI)
Lumbar puncture
EEG

Question 10

Contents of CSF with bacterial infection

Answer 10

Cloudy

High pressure

High protein

Low glucose

High WC count (neutrophils)

Question 11

Contents of CSF with viral infection

Answer 11

Clear

normal glucose

High WC count (lymphocytes)

Question 12

Symptoms of brain abscess

Answer 12

Fever

Headache

Raised ICP

Features of likely infection (dental, sinus, ear)