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Med Surg > CNS DEPRESSANTS > Flashcards

CNS DEPRESSANTS Flashcards

1
Q

SEDATTIVES

A

CNS will inhibit them -

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2
Q

CNS DEPERSSANTS

A

think of ALCHOL

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3
Q

HYPONTICS

A

make you sleepy more potent effect on CNS , meant to cause SLEEP

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4
Q

SEDATIVE-HYPONTIC

A

Dose dependent small doses chill you out high dose will SLEEP

  1. Barbiturates
  2. Benzos
  3. Miscalleneous drugs
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5
Q

SLEEP

A

cyclir repeptative unware or sensory stimuli of immediated envoiroment , not conciusly aware

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6
Q

SLEEP ARCHITETURES

A 
RAPID EYE( REM) 
Non - REM sleep
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7
Q

BENZODIAZEPINES

A

sedative hypnotic drugs now we go for non benzodiazepine
Sedative hypnotic
Anziolytic- decrease anxity

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8
Q

BENZO: SEDATIVE HYPNOTIC

A 
long acting: CLONZEPAM (klnopan) DIAZEPAM (Valium) 
Intermediate  acting (alprazpam- Xanax LORAZEPAN Ativan 
Short acting: zolpidem(AMbien)  Midazolam(Versed)  Lunseda
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9
Q

BENZO: MECHANSIM OF ACTION

A

depress CNS
GABA
don’t suppress rapid eye movement effect Quality of sleep (don’t increase metabolism of other drugs)
decrease of interactions

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10
Q

BENZO: DRUG EFFECTS

A

induce sleep , relax and agitation inducing USE FOR SKELTAL PAIN

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11
Q

BENZO: INDICATIONS

A

HELP FALL ASLEEP , SEDATION MUSCLE RELXERS ANXIETY, VERSCED(ACUTE SEIZURE) CIWA BALANCE ANETHESIA CONCIOUS SEDATION (BONE RESETTING COLONSCOPY)

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12
Q

BENSO: SIDE AFFECT

A

HEADACHE DROWISNESS DIZZNESS DAY TIME HANG OVER EFFECT SLEEPINES (FALL RISK)

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13
Q

BENZO: TOXICITY OVERDOSE AND INTERACTIONS

A

CONFUSION SOMOLENCE COMA DIMINISHED REFLEX BENZO WITH ALOCHOL = RESPIRATORY DEPRESSION
FLUMAZENIL IS ANTIDOTE
INTERACT WITH ANITFUNGIL ABT , GRAPEFRUIT JUICE INTERACT WITH OTHER CNS DEPPRESANTS, RIFAMPIN

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14
Q

DIAZEPMA (VALIUM)

A

ANXIETY OR MUSCLE RELAXER

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15
Q

MIDAXOLAM(VERSED)

A

AGIGATION AND SEDATION (ORHTO PROCEDURES

)INJECTION IN ADULTS RECTALLY IN KIDS OR LIQUID

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16
Q

TEMAZEPAM RESTORIL

A

takes a while to work take an 1hour before you go to bed

17
Q

LUNESTA: nonbenzo

A

need 8 hours of sleep time if need to wake uo in 6 hours then shouldnt take

18
Q

RAMELTEON(ROZEREM): NONBENZO

A

NOT KEEP ASLEEP HELP FALL ASLEEP

19
Q

ZALEPHON: SONAATA

A

ONLY WORKS 4 HOURS

20
Q

ZOLPIDEM(AMBIEN)

A

SHORT ACTING : NOT DAYTIME SLEEPINESS ONE NOW AND RELEASES SOME LATER
CAUSES SLEEP WALKING

21
Q

KAVA

A

HELP FALL ASLEEP CAN CAUSE YOU TO TURN YELLOW DONT TAKE IF HAVE LIVER IMPARIMENT

22
Q

VALERIAN

A

CAN CAUSE RESTLESSNES AND ANXITY INTERACTS WITH MAOI ALCHOL INTERACTS WITH LIVER ADN CARDIAC ISSUES (yellow skin) may cause insomnia

23
Q

BARBITURES

A

STANDARD - HABIT FORMING DOSENT TAKE ALLOT FOR THEM TO WORK
work in the brain stem inhibit nerve stem from geeting in the brain
Drug effects: high doses lower RESPITORY RATE
stimulate liver enzymes (drugs don’t last as long in system)
low therapeutic index: the effective safe dosage range is narrow only a little bit before the become toxic

24
Q

BARBITUES INDICATIONS

A 
sedatives 
anticonvulsants 
seizures 
1. ultrashort- surgical procedures 
short acting - sedation convulsant 
intermediate  sedation and convulsant 
long acting - sleep induction and seizures
25
Q

BARBITUES ADVERSE EFFECTS

A

vasodilation and hypotension drowsiness , resp depression COUGH, agranulocytosis , risk for platelets
STEVEN JOHNSON , reduce REM sleep
OLD PATIENTS- START LOW AND GO SLOW

26
Q

BARBTUES TOXICITY

A

OVERDOSE LEADS TO DEPRESSION

OVERDOSE- VENTILLLATOR , VASOPRESSIN, FLUIDS AND CHAROCAL

27
Q

INTERACTIONS

A

ADDITIVE EFFECTS - alcohol ,antihistamine, benzo opiods tranquilizers , inhibited metabolism MAOIs prolonged
increased metabolism reduces anticoargulant response leading to possible clot formation

28
Q

Phenorbital (Nembutal)

A

long acting - generalized seizures status epelicuts preserve brain function and provide oxygen sedate them

29
Q

over the counter

A

non prescription sleep aids CNS depressant effect - tylenol PM Sominex
if use with alchol could have respiratory effect

Med Surg (9 decks)

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