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Pharmacology > Cns,chemo,psyche > Flashcards

Cns,chemo,psyche Flashcards

1
Q

What are the categories of psychotropic medications?

A

Antidepressants, Anti-anxiety agents, Stimulant drugs, Typical antipsychotics, Atypical antipsychotics, Mood stabilizers.

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2
Q

What is the first line treatment for depression?

A

SSRI (Selective serotonin reuptake inhibitors)

Common drugs include Citalopram, Fluoxetine, and Sertraline.

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3
Q

What is a common drug for SNRIs?

A

Duloxetine.

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4
Q

What do MAOIs do?

A

Increase dopamine, norepinephrine, and serotonin levels in the brain.

Avoid dairy products like cheese, wine, and pickles.

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5
Q

What is a common drug for MAOIs?

A

Isocarboxazid.

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6
Q

What is a common drug for Tricyclic antidepressants?

A

Amitriptyline.

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7
Q

What are anti-anxiety agents used for?

A

Anxiety and seizures (short term use).

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8
Q

What are common benzodiazepines?

A

Diazepam, Lorazepam, Clonazepam, Temazepam, Alprazolam, Midazolam.

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9
Q

What is a common stimulant drug?

A

Amphetamine.

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10
Q

What are common typical antipsychotic drugs?

A

Haloperidol, Chlorpromazine.

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11
Q

What are common atypical antipsychotic drugs?

A

Clozapine, Olonzapine, Quetiapine.

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12
Q

What are common mood stabilizer drugs?

A

Carbamazepine, Sodium Valproate, Phenytoin, Phenobarbital.

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13
Q

barbiturate

A

phenobarbital
amobarbital
secobarbital
primidone

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14
Q

types of chemotherapy

A

1.curative- long term/complete eradicate cancer cell
2.adjuvant- preventive/after surgery
3.neoadjuvant- prior to cancerous/before the surgery to help more manageable to treat
4. palliative- symptomatic management

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15
Q

Anti cancer drugs classification

A

cytotoxic - antineoplastics/kill cancer cell
non cytotoxic- do not primarily work by killing cells

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16
Q

Cytotoxic

A

1.antimetabolites
2.antitumor antibiotics
3.plant alkaloids
4.alkylating agents

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17
Q

antimetabolites

A

folate antagonists
pyrimidine analogs
purine analogs
ribonucleotide reductase inhibitors

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18
Q

Antitumor antibiotics

A

anthracyclines
other antitumor antibiotics

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19
Q

Antitumor antibiotics

A

anthracyclines
other antitumor antibiotics

20
Q

plant alkaloids

A

vinca alkaloids
taxanes
camptothecins
podophyllotoxins

21
Q

SNRI

A

Serotonin-norepinephrine reuptake inhibitors

22
Q

SSRI

A

Selective serotonin reuptake inhibitors

23
Q

Drug classification of CNS

A

Cns depressant
Cns stimulant

24
Q

Cns depressant

A

benzodiazepine
barbiturate
anesthetics

25
Q

Benzodiazepine

A

works by increasing effect of the neurotransmitter called gamma-aminobutyric acid
(GABA) in the brain. GABA is inhibitory neurotransmitter that reduces brain activity

Drugs:Diazepam

Lorazepam

Clonazepam

Temazepam

• Alprazolam

• Midazolam

26
Q

Barbiturate

A

Act directly on GABA (gamma-aminobutyric acid receptors, keeping them open for an extended period, leading to a negative charge and reduced nerve cell responsiveness.
Drugs:
• Phenobarbital
• Amobarbital
• Secobarbital
• Primidone

27
Q

Local anesthetics

A

Lidocaine
Procaine
Bupivacaine

28
Q

General anesthetics

A

Propofol
Sevoflurane

29
Q

Cns Stimulant

A

Anorexiants
anti-epileptic
analgesic

30
Q

anorexiants

A

to promote weight loss through appetite suppressant and stimulation effects by increasing norepinephrine availability to neural receptors
Drugs:
• Phentermine
• Orlistat
• Lorcaserin
Common side effect; increased bp & hr

31
Q

Anti-epileptic drugs

A

stabilizing neuronal membranes and reducing abnormal electrical activity in the brain, preventing seizures

Drugs:
Carbamazepine
• Phenytoin
• Valproic Acid

32
Q

analgesic 2 types

A

anti inflammatory ( Non-steriodal anti inflammatory drugs)
Opioids

33
Q

anti inflammatory

A

ibuprofen
naproxen
aspirin
diclofenac
celecoxib

34
Q

Opioids

A

morphine
diamorphine
oxycodone,hydromorphone
fentanyl
tapentadol

35
Q

common side effect of nsaid

A

gastrointestinal issue

36
Q

common side effect of nsaid

A

gastrointestinal issue

37
Q

common side effect of opioids

A

constipation, nausea

38
Q

common side effect of acetaminophen

A

liver toxicity

39
Q

opiod antagonist

A

naloxone- for opiod overdose and toxicity

40
Q

opioid agonist

A

methadone or buprenorphine

41
Q

PNS stimulant

A

Anti-cholinergic
Acetylcholinesterase/Cholinesterase inhibitors
Neuromuscular blocking agents
muscle relaxants

42
Q

Anti cholinergic

A

block the action of the neurotransmitter acetylcholine, inhibiting the effects on various organ system.
Drugs:
• Atropine
• Scopolamine
• Benztropine

Common side effect; Reduce salivation, muscle tremors and increased HR

43
Q

Anti cholinergic

A

block the action of the neurotransmitter acetylcholine, inhibiting the effects on various organ system.
Drugs:
• Atropine
• Scopolamine
• Benztropine

Common side effect; Reduce salivation, muscle tremors and increased HR

44
Q

Acetylcholinesterase

A

inhibiting the enzyme acetylcholinesterase, breaks down the neurotransmitter acetylcholine in the brain (Alzheimer’s diseases)
Drugs:

Donezepil
Rivastigmine

Common side effect: nausea, vomiting, diarrhea, bradycardia and muscle weakness

45
Q

Neuromuscular blocking agents

A

Succinylcholine
Rocuronium

drugs that paralyze muscles to help with anesthesia, intubation, and mechanical ventilation

Drugs:
• Succinylcholine
• Rocuronium

Common side effect; paralysis, changes in BP and HR, potential allergic reactions

46
Q

Muscle relaxants

A

act in the central nervous system to reduce tension and spasm of the skeletal muscles.
Drugs:
• Succinylcholine
• Rocuronium
Methocarbamol, Baclofen, Cyclobenzaprine, Tizanidine
Carisoprodol, Chlorzoxazone, Dantrolene, Metaxalone,

Pharmacology (4 decks)

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