CNS Flashcards
neuroglial cells
astrocytes
microglial
oligodendroglia
ependymal cells
causes for cerebral edema
trauma
bacterial or viral infection
hemmorrhage
cerebral edema can be either
vasogenic or cytotoxic
vasogenic edema is
extravascular accumulation of fluid due to its leakage across damaged wall (necrotic lesion, abcess, tumor); due to new capillary bed formation secondary to lack of good BBB
cytotoxic edema is
intracellular accumulation of fluid such as ischemia, toxin, or hypoxia –> impair cell wall function
pathology of cerebral edema
flat gyri, decreased demarcation between gray and white matter, slitlike sulci, swollen and heavier, brain herniation
clinically patient will present with what symptoms when having cerebral edema?
headache, papilledema, vomiting, due to increase of intracranial pressure
hyodrocepphalus has two categories
non-communicating and communicating
in non-communicating hydrocephalus is (obstructive) what cannot reach the subarachnoid space?
CSF
2 types of congenital non-communicating hydrocephalus
arnold chiari malformation
&
stenosis of aqueduct of sylvius or foramina of ventricles (CSF cannot reach 4 & 3rd ventricles)
arnold chiari is when the
cerebellar tonsil’s are displaced into the cervical canal through the foramen magnum
cerebellar tonsilar herniation will cause what clinically?
flattening of base of skull and hydrocephalus is present
acquired hydrocephalus types
inflammation - meningitis secondary to fibrosis, cerebral abcess
tumors
intracranial hemorrhage
acquired hydrocephalus by inflammation is caused frequently by
inflammation - meningitis secondary to fibrosis, cerebral abcess
acquired hydrocephalus by tumors is caused frequently by
ependymoma & medullablastoma
communicating hydrocephalus is due to
a blockage within the subarachnoid space
what kind of blockage can cause communicating hydrocephalus?
dural venous thrombosus
1 cause of cerebral infarction
embolism
which cerebral atery is most involved in embolism?
middle cerebral artery which is a direct extension of ICA
what type of infarct is one caused by embolism?
pale white anemic
what kind of infarct is caused by hypertension?
red hemmorragic
what is the 2nd leading cause of cerebral infarct?
ATH of the carotid, basilar, middle or cerebral artery
a detached mural thrombus from the _____ atrium will travel to
left
middle cerebral artery
types of cerebral herniation
subfalcine (cingulate)
uncinate (transtentorial)
tonsillar
subfalcine aka cingulate herniation is where
the cingulate gyrus ruptures and travels across the falx cerebri and ruptures the anterior cerebral arteries
uncinate AKA the transtentoral herniation is where
CN III is is affected
loss of consciousness
compression of aqueduct sylvius
CN III compression by uncinate herniation will present clincally as
dilaiton of pupil, impaired eye movement on same side resulting in suqinting of eyes, eyes move seperately and parasympathetic disruption
tonsilar herniation is when
the cerebrllar tonsils go through the foramen magnum –> compression of the medulla and cardiorespiratory center leading to death