CNS Flashcards
Meningitis likely pathogens in neonates
listeria
GBS
E.coli
Meningitis likely pathogens age 10-21
Neisseria meningitidis
Meningitis likely pathogens age >21
Strep pneumoniae
Neisseria meningitidis
Meningitis likely pathogens >65
Strep pneumoniae
Listeria
Groups of patients likely to get Listeria meningitis
Neonates
Elderly (>60)
Immunocompromised
Likely pathogen in meningitis following fracture of cribriform plate
Strep pneumoniae
Encephalitis likely pathogen
Herpes simplex
Empirical treatment of meningitis
IV Ceftriaxone 2g bd + IV Dexamethasone
Treatment in encephalitis suspected
IV Aciclovir
Treatment if Listeria suspected
Add IV Amoxicillin/Ampicillin
resistant to cefriaxone
Describe the typical CSF findings in a viral meningitis including cell type, protein and glucose:
Lymphocytes
Protein normal or slightly raised
Glucose usually normal
Describe the typical CSF findings in a bacterial meningitis including cell type, protein and glucose:
Neutrophils
Protein high
Glucose < 70% of blood glucose
Describe the typical CSF findings in a TB meningitis including cell type, protein and glucose:
Predominantly lymphocytes
Protein high or very high
Glucose < 60% of blood glucose
Which patients should have a CT prior to lumbar puncture?
Immunocompromised History of CNS disease New onset seizure Papilloedema Reduced GCS Focal neurological deficit
Which antibiotic is given as contact prophylaxis for meningitis?
Single dose ciprofloxacin