CMRI Flashcards

1
Q

What are the 5 areas of emphasis of the CMRI?

A
  1. Genomic Medicine
  2. Precision Therapeutics
  3. Health Care Innovation
  4. Emerging Infections
  5. Population Health
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2
Q

When did the CMRI officially open?

A

February 18th, 2021

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3
Q

Physical space of CMRI?

(# of stories and sq. footage)

A

9-Story
375,000 sq ft

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4
Q

What is the goal of CMRI?

A

Accelerate precise diagnoses and treatments for complex and rare childhood diseases (moving children to the forefront of research discoveries)

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5
Q

Genomic Medicine

Definition & Location in CMRI

A
  1. Supports clinical whole-genome sequencing integrated with data from epigenome, single-cell omics, liquid biopsies, and genome editing to advance full human genome analysis
  2. Located on the 3rd floor of the CMRI
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6
Q

Precision Therapeutics

Definition & Location in CMRI

A
  1. Uses patient-specific information to optimize treatment for individual patients through a transdisciplinary research approach
  2. Located on the 3rd floor of the CMRI
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7
Q

Health Care Innovation

(Description)

A

Identifies, articulates, and advances products and processes that optimize the medical, surgical, and therapeutic management of children

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8
Q

Emerging Infections

(Description)

A

Enhancing the ability to handle current and emerging infectious diseases to protect children and public health

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9
Q

Population Health

Definition & Location in CMRI

A
  1. Uses transdisciplinary research to generate new knowledge on the personal, social, economic, and environmental factors that influence the distribution of health outcomes and the evaluation of interventions and policies to improve those outcomes
  2. Located on the 2nd floor of the CMRI
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10
Q

Infectious Disease

Definition & Location in CMRI

A

Disorders that are caused by organisms - such as bacteria, viruses, fungi and parasites
Located on the 7th floor of CMRI

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11
Q

Vivarium/Shelled Space

Definition & Location in CMRI

A

Space adapted/prepared for keeping animals under seminatural conditions for observation & study
Located on the 6th floor of CMRI
DO NOT SHARE WITH VISITORS - ONLY SHARE AS SHELVED SPACE

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12
Q

Oncology

Definition & Location in CMRI

A

Deals with diagnosis, treatment, prevention, and early detection of cancer
Located on the 4th floor of CMRI

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13
Q

Immunology Lab

Definition & Location in CMRI

A
  1. Finding antibodies (proteins made by a type of white blood cell) in response to an antigen (foreign substance) in the body
  2. Studying problems with the Immune System - including when the body’s immune system attacks its own tissues
  3. Located on the 4th floor of CMRI
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14
Q

Good Manufacturing Practice (GMP Facility)

Definition & Location in CMRI

A
  1. Manufacturing Faciltiy that meets industry-standard quality specifications
  2. Reduces risk in producing supplements & pharmaceuticals
  3. Maintaining a clean and hygienic manufacturing area, controlling environmental conditions, and definining and controlling manufacturing processes
  4. Located on the 4th floor of CMRI
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15
Q

Biological Safety Level III Facility

Definition & Location in CMRI

A
  1. Used to study infectious agents or toxins that may be transmitted through the air and cause potentially lethal infections
  2. Researchers perform all experiments in a biosafety cabinet - designed to be easily decontaminated
  3. Located on the 4th floor of the CMRI
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16
Q

Nephrology

Definition & Location in CMRI

A
  1. Branch of internal medicene that deals with kidney deiseases and disorders
  2. Located on the 4th floor of the CMRI
17
Q

Wet Lab

Definition & Location in CMRI

A
  1. Laboratory where testing and analyses are performed using physical samples, chemicals, and liquids
  2. Biological samples, drugs and fluids (“Wet” materials)
  3. Located on the 3rd floor of CMRI
18
Q

Clinical Pharmacology

Definition & Location in CMRI

A
  1. Teaches, researches, frames policies, gives informaiton and advice about the actions and proper uses of medicines in humans and implements that knowledge in clinical practice
  2. Experimental and observational study of the disposition and effects of drugs in humans, and committed to the translation of science into evidence-based therapeutics
  3. Discovery of new target molecules to the effects of drug usage in whole populations - broad scope
  4. Generate data for optimum use of drugs and the practice of ‘evidence-based medicine’
  5. Located on the 3rd floor of CMRI
19
Q

Dry Lab

Definition & Location in CMRI

A
  1. Testing and analyses is performed using data, coding and computer systems (modeling and analysis)
  2. Methodology, analysis of wet lab test results, data analysis, coding, text interpretation
  3. Located on the 2nd floor of CMRI
20
Q

Reserach Informatics

Definition & Location in CMRI

A
  1. Storing, managing, or reporting on data used for research purposes (clinical and basic scientific research)
  2. Located on the 2nd floor of the CMRI
21
Q

Bioethics

Definition & Location in CMRI

A
  1. Field of study that examines the mroal and ethical questions arising in medicine and the life sciences
  2. human life and well being, and the ethical questions relating to the nonhuman biological environment
  3. Three main sub-disciplines (medical ethics, animal ethics, and environmental ethics)
  4. Located on the 2nd floor of the CMRI
22
Q

Endocrinology

Definition & Location in CMRI

A
  1. Subspecialty of internal medicine that treats diseases related to problems with hormones
  2. Hormones secreted by endocrine glands (pituitary, thyroid or adrenal)
  3. Located on the 2nd floor of the CMRI
23
Q

Innovation in Healthcare

Definition & Location in CMRI

A
  1. Quest for knowledge, with a passion to find answers (curiosity value)
  2. Build institutional infrastructures and processes to enable efficient solution development capabilities that benefit our patients & families
  3. Creating new sustainability and commercialization models
  4. PedsGuide, MyCare, MyMeidcal Art, Ocurate (concussion pen)
  5. Located on the 2nd floor of the CMRI
24
Q

1st Floor of CMRI

A
  1. CMRI Conference Center
  2. Discovery Cafe
  3. Main Donor Wall
  4. Research Administration
  5. Office of Research Integrity
  6. Research Compliance
25
Q

Garden Level of CMRI

A

Rooftop Garden

26
Q

Outside the CMRI

A
  1. Glass window DNA sequence
  2. White pylons recognizing staff donations to research
  3. Connection to the hospital and POB (to highlight bench to bedside collaboration)