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Microbiology > Cluster of Differentiations > Flashcards

Cluster of Differentiations Flashcards

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Biology 101 flashcards
1
Q

What are CD’s

A

they are the main cell surface receptors

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2
Q

CD2 Function *LFA-2

A

adhesion molecule

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3
Q

CD3 Function

A

signal transduction by TCR

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4
Q

CD4 Function

A

Co receptor MHCII, HIV

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5
Q

CD8 Function

A

Co receptor MHC I

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6
Q

CD 14 Function *LPS Receptor

A

Binds LPS, epithelioid cells in the granulomatous lesions of leprosy are CD14 cells

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7
Q

CD16 (Fc Receptors) Function

A

Opsonization ADCC

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8
Q

CD18 Functions

A

Cell Adhesion Molecule

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9
Q

CD19 Functions

A

Co receptor with CD 21 for B cell, activation for signal transduction

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10
Q

CD20 Function

A

B cell activation

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11
Q

CD21 (CR2, C3d Receptor) Function

A

C3d receptor with CD19, Epstein-Barr virus receptor

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12
Q

CD25 Function

A

Alpha chain of IL-2 receptor

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13
Q

CD28 Function

A

T-cell receptor for costimulatory molecule B7

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14
Q

CD34 Function

A

Cells-cell adhesion, binds L-section

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15
Q

CD40 Function

A

Binds CD40L, role in T cells dependent B cell, macrophage, dendritic cell and endothelial cell activation

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16
Q

CD2 Cellular Expression

A

T cells, Thymocytes, NK cells

17
Q

CD3 Cellular Expression

A

T cells, Thymocytes

18
Q

CD4 Cellular Expression

A

TH Cells, Thymocytes, Monocytes/Macrophages

19
Q

CD8 Cellular Expression

A

CTLs, some Thymocytes

20
Q

CD14 Cellular Expression

A

Monocytes, Granulocytes

21
Q

CD16 Cellular Expression

A

NK Cells, Macrophages, Neutrophils

22
Q

CD18 Cellular Expression

A

Leukocytes

23
Q

CD19 Cellular Expression

A

B cells

24
Q

CD20 Cellular Expression

A

B cells

25
Q

CD21 Cellular Expression

A

Mature B cells

26
Q

CD25 Cellular Expression

A

Activated TH Cells and Treg Cells

27
Q

CD28 Cellular Expression

A

T Cells

28
Q

CD34 Cellular Expression

A

Precursors of hematopoietic cells, endothelial cells

29
Q

CD40 Cellular Expression

A

B cells, Macrophages, Dendritic Cells, Endothelial Cells

30
Q

Which myeloid cells are CD 14 positive (4)

A

Monocyte
Macrophage
Neutrophil
Dendritic

31
Q

Which myeloid cells are CD 16 and CD 56 positive (1)

A

NK Lymphocyte

Microbiology (3 decks)

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