Clotting Flashcards

1
Q

Platelet granule contents

A

Fibrinogen, vWF, Factor V, Calcium, Serotonin, Plasminogen, Platelet factor 4

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2
Q

Functions of thrombin

A
Fibrinogen to Fibrin
FXI, FXIII
Cofactor V VIII activation
Protein C pathway
Platelet aggregation
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3
Q

FVIII Phsysiology

A

Produced primarily in hepatocytes
Extremenly unstable except when bound to vWF
Binds with FIX and vWF in coagulation complex

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