Clopidogrel Flashcards
0
Q
Brand name
A
Placid
1
Q
Generic name
A
Clopidogrel
2
Q
Drug class
A
Threnody riding antiplatelet
3
Q
Mechanism of action
A
Inhibits platelet aggregation by blocking activation of the glycoprotein IIb/IIIa complex
4
Q
Indications
A
ST elevation MI (STEMI), moderate to high risk non-ST elevation MI (STEMI), acute coronary syndrome, substitute for aspirin in pts. Unable to take aspirin.
5
Q
Contraindications
A
Active GI bleeding
intracranial hemorrhage
known hypersensitivity
6
Q
Adverse effects
A
Severe neutropenia Thrombotic thrombocytopenic purpurin (TTP) GI hemorrhage Cerebral hemorrhage Antioedema Stevens-Johnson syndrome Rash Flulike syndrome
7
Q
Precautions
A
Should not be taken with proton pump inhibitors (omeprazole and similar drugs), use with caution with other anticoagulants (Warfarin, enoxaparin, streptokinase, aspirin).
8
Q
Dose and administration
A
Adult: Loading dose 300-600mg PO
Pediatric: not recommended
