Clinical Skill/Critical Care in NC_2 Flashcards
- Which of the following disorders leads to hypernatremia?
a. Addison’s disease
b. hyperaldosteronism
c. hypothyroidism
d. renal failure
e. syndrome of inappropriate antidiuretic hormone (SIADH)
B. hyperaldosteronism
22 The most common acid-base disturbance in mild to moderately injured patients without severe renal, circulatory, or pulmonary decompensation is
a. respiratory acidosis and metabolic alkalosis
b. respiratory alkalosis and metabolic acidosis
c. respiratory or metabolic acidosis
d. respiratory or metabolic alkalosis
D. respiratory or metabolic alkalosis
- The reabsorption of Na+ ions in the thin ascending Henle’s loop
a. is by active transport
b. is by a Na+-K+ exchange pump
c. passively follows the active transport of CI- ions
d. passively follows the active transport of water molecules
C. passively follows the active transport of CI- ions
24. Of the two prodrugs that block the Gi-coupled platelet adenosine diphosphate (ADP) receptor, it has a slightly more favorable toxicity profile. A. abciximab (Reopro) B. aspirin C clopidogrel (Plavix) D. eptifibatide (Integrilin) E. ticlopidine (Ticlid)
C. clopidogrel (Plavix)
25. is the Fab fragment of a monoclonal antibody directed against the IIb/IIIa receptor A. abciximab (Reopro) B. aspirin C clopidogrel (Plavix) D. eptifibatide (Integrilin) E. ticlopidine (Ticlid)
A. abciximab (Reopro)
is a cyclic peptide inhibitor of the arginine-glycine-aspartate (RGD) binding site on the glycoprotein IIb/lIIa A. abciximab (Reopro) B. aspirin C clopidogrel (Plavix) D. eptifibatide (Integrilin) E. ticlopidine (Ticlid)
D. eptifibatide (Integrilin)
blocks production of thromboxane A2 A. abciximab (Reopro) B. aspirin C clopidogrel (Plavix) D. eptifibatide (Integrilin) E. ticlopidine (Ticlid)
B. aspirin
Which laboratory findings in disseminated intravascular coagulation (DIC)
correlates most closely with bleeding?
A. decreased fibrinogen
B. increased fibrin degradation products
C. increased prothrombin time (PT)
D. increased partial thromboplastin time (PTT)
E. increased thrombin time (TT)
A. decreased fibrinogen
The definition of oxygen saturation is the
A. amount of oxygen dissolved in plasma
B. fractional concentration of inspired oxygen
C. partial pressure of oxygen in the blood
D. percentage of hemoglobin that is bound to oxygen
E. ratio of unbound to bound hemoglobin
D. percentage of hemoglobin that is bound to oxygen
Metabolic responses to trauma include each of the following except A. hypoglycemia B. increased rate of lipolysis C. increased Na+ reabsorption D. increased water reabsorption E. metabolic'alkalosis
A. hypoglycemia
A normal PT, a prolonged PTT, and a bleeding disorder would result from a deficiency of factor A. II B. V C. VIII D. X E. XII
C. VIII
shortest half-life A. factor II B. factor VII C. factor VIII . D. factor IX E. factor X
B. factor VII
reflects the extrinsic pathway A. factor II B. factor VII C. factor VIII . D. factor IX E. factor X
B. factor VII
deficient or abnormal in hemophilia A (classic) A. factor II B. factor VII C. factor VIII . D. factor IX E. factor X
C. factor VIII .
deficient in hemophilia B (Christmas disease) A. factor II B. factor VII C. factor VIII . D. factor IX E. factor X
D. factor IX