Clinical questions Flashcards

1
Q

Which way does the blood flow throw the heart?

A

Right Atrium
Right Ventricle
Lungs
Left Atrium
Left Ventricle
Body

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2
Q

What is the first heart sound? S1

A

beginning of ventricular systole (contraction)

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3
Q

What is the second heart sound? S2

A

end of ventricular systole

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4
Q

What is the third heart sound? S3

A

There is NO 3rd heart sound. It is called a murmur and its abnormal caused by turbulent blood flow or reguritation

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5
Q

What are some symptoms that come with arrhythmias?

A

heart “fluttering”
dizziness, SOB, fatigue, lightheadedness, chest pain*

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6
Q

What is the route of the heart beat neurologically?

A

begins in Sinoatrial (SA) node (pacemaker) in the RIGHT atrium
- this causes the impulse to travel through both atria signaling them to contract

Then signal reaches atrioventricular (AV node) continuing down into the bundle of His

The bundle of His splits off into two:
left - for the left ventricle
right - for the right ventricle

Then the signal reaches the Purkinje fibers which cause the ventricles to contract

***any disruption in the sequence of impulse conduction results in an arrhythmia

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7
Q

What structure controls the rate and rhythm of the heart beat?

A

sinoatrial node (SA)

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8
Q

What could be some structural or conduction changes that cause arrthymias?

A

-SA node fires at abnormal rate or rhythm
-Scar tissue from MI causing diversion of a signal
-AV node acting as the pacemaker instead of the SA node

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9
Q

The pacemaker initiates its own action potential. What are the phases of this actional potential?

A

Phase 0: rapid ventricular depolarization responding to an influx of Na+ === causes the ventricular contraction later
Phase 1: Na+ channels close
Phase 2: slow influx of Ca and efflux K
Phase 3: RAPID ventricular repolarization from rapid K efflix= Ventricular relaxation
Phase 4: resting membrane potential and when the atrial is depolarized

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10
Q

On an ECG, what do the different waves mean in regard to action potential?

A

P wave - atrial contraction from phase 4 (resting membrane potential)

QRS complex - ventricular contraction from phase 0 (influx of Na+)

T wave - ventricular relaxation from phase 3 (rapid efflux of K+)

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11
Q

What are the common causes of arrhythmias?

A
  • Mycardial infarction
  • Electrolyte imbalances
  • elevated sympathetis states (hyperthyroidism, infection)
  • drugs that prolong QTc or stimulants (illicit drugs)
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12
Q

What are the two classifications of arrythmias andwhere do they originate?

A

Supraventricular (above the AV node)
Ventricular (below the AV node)

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13
Q

Examples of Supraventricular Arrhythmias

A

Sinus Tachycardia
Atrial Fibrillation
Atrial Flutter
Atrial Tachycardia
Supracentricular Tachycardias (SVT)

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14
Q

Examples of Ventricular Arrhythmias

A

Premature Ventricular Contraction (PVC)
Ventricular Tachycardia
Ventricular Fibrillation

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15
Q

Premature Ventricular Contraction (PVC)

A

“skipped heartbeat” generated within ventricluar tissue and can be related to stress or too much caffeine

COMMON

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16
Q

Ventricular Tachycardia

A

A series of PVS resuling in HR > 100 bpm

can be pulseless VT = MEDICAL EMERGENCY

17
Q

Ventricular Fibrillation

A

completely disorganized electrical activation of the ventricles

MEDICAL EMERGENCY

18
Q

Atrial flutter

A

more organized and regular compared to afib

19
Q

Atrial Fibrillation

A

multiple waves entter the atria causing irregular ventricular response

20
Q

Drugs causing prolonged QTc

A

Antiarrhytmics
Antimalarials
Azoles
Macrolides
Quinolones
Antidepressants (SSRI, TCA, Mirtazapine, Trazadone, Venlafaxine)
Antiemetics (5-HT3 antagonists, Droperidol, Metoclopromide, Promethazine)
Antipsychotics (1st gen and 2nd gen)
**highest risk with ziprasidone)
Oncology (TKI, androgen deprivation ex: leuprolide, Oxaliplatin)

21
Q

Paroxysmal AF

A

AF that terminates spontaneously or with intervention within 7 days of onset; may reoccur

22
Q

Persistent AF

A

Continuous AF that is sustaned > 7 days

23
Q

Long-standing AF

A

Continuous AF that is sistained > 12 months

24
Q

Valvular AF

A

AF with mechanical heart valvue; long term warfarin is indicated

25
Q

What is the goal HR for patients with symptomatic AF?

A

< 80 bpm

26
Q

What is an appropriate HR goal for AF patientws with no symptoms and have preserved left ventricular function?

A

< 110 bpm

27
Q

What is the most effective method to revert to normal sinus rhythm?

A

Cardioversion - delivers a high-energy shock through the chest wall

RISKS: thromboembolism –start anticoagation at least 3 weeks before to prevent

28
Q

What medications may be used to convert to normal sinus rhythm as pharmacologic cardioversion?

A

Class III:
Amiodarone
Dofetilide
Ibutilide

Class 1c:
Flecainide
Propafenone

29
Q

What medications may be used to maintain normal sinus rhythm?

A

Class III:
Dofetilide
Dronedarone
Sotalol

Class1c:
Flecainide
Propafenone

**amiodarone only recommended when other drugs have failed or contraindicated due to toxicities!